S
Simon P. Hoerstrup
Researcher at University of Zurich
Publications - 272
Citations - 13184
Simon P. Hoerstrup is an academic researcher from University of Zurich. The author has contributed to research in topics: Tissue engineering & Heart valve. The author has an hindex of 61, co-authored 258 publications receiving 11938 citations. Previous affiliations of Simon P. Hoerstrup include Harvard University & Wyss Institute for Biologically Inspired Engineering.
Papers
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Journal ArticleDOI
Functional Living Trileaflet Heart Valves Grown In Vitro
Simon P. Hoerstrup,Ralf Sodian,Sabine Daebritz,Jun Wang,Emile A. Bacha,David P. Martin,Adrian M. Moran,Kristine J. Guleserian,Jason S. Sperling,Sunjay Kaushal,Joseph P. Vacanti,Frederick J. Schoen,John E. Mayer +12 more
TL;DR: In vitro generation of implantable complete living heart valves based on a biomimetic flow culture system that functioned up to 5 months and resembled normal heart valves in microstructure, mechanical properties, and extracellular matrix formation.
Journal ArticleDOI
Fibrin gel as a three dimensional matrix in cardiovascular tissue engineering
Qing Ye,Gregor Zünd,Peter Benedikt,Stefan Jockenhoevel,Simon P. Hoerstrup,Shelly Sakyama,Jeffrey A. Hubbell,Marko Turina +7 more
TL;DR: A three-dimensional fibrin gel structure can serve as a useful scaffold for tissue engineering with controlled degradation, excellent seeding effects and good tissue development.
Journal ArticleDOI
Early In Vivo Experience With Tissue-Engineered Trileaflet Heart Valves
Ralf Sodian,Simon P. Hoerstrup,Jason S. Sperling,Sabine Daebritz,David P. Martin,Adrian M. Moran,Byung S. Kim,Frederick J. Schoen,Joseph P. Vacanti,John E. Mayer +9 more
TL;DR: Tissue-engineered heart valve scaffolds fabricated from polyhydroxyalkanoates can be used for implantation in the pulmonary position with an appropriate function for 120 days in lambs.
Journal ArticleDOI
Fibrin gel -- advantages of a new scaffold in cardiovascular tissue engineering.
Stefan Jockenhoevel,Gregor Zünd,Simon P. Hoerstrup,K. Chalabi,Jörg S. Sachweh,L. Demircan,Bruno J. Messmer,Marko Turina +7 more
TL;DR: Fibrin gel combines a number of important properties of an ideal scaffold and can be produced as a complete autologous scaffold that is moldable and degradation is controllable by the use of aprotinin.
Journal ArticleDOI
Tissue engineering of small caliber vascular grafts
TL;DR: The feasibility of tissue engineering of viable, surgically implantable small caliber vascular grafts and the important effect of a 'biomimetic' in vitro environment on tissue maturation and extracellular matrix formation are demonstrated.