S
Siu Ha Lau
Researcher at Manchester Royal Infirmary
Publications - 3
Citations - 397
Siu Ha Lau is an academic researcher from Manchester Royal Infirmary. The author has contributed to research in topics: Multilocus sequence typing & Typing. The author has an hindex of 3, co-authored 3 publications receiving 380 citations.
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Journal ArticleDOI
Major Uropathogenic Escherichia coli Strain Isolated in the Northwest of England Identified by Multilocus Sequence Typing
Siu Ha Lau,Suganya Reddy,John Cheesbrough,F. J. Bolton,Geraldine A. Willshaw,Tom Cheasty,Andrew J. Fox,Mathew Upton +7 more
TL;DR: MLST has identified an important genetic lineage of E. coli, designated sequence type 131 (ST-131), represented by 52 of these isolates, 51 of which were resistant to extended-spectrum cephalosporins.
Journal ArticleDOI
UK epidemic Escherichia coli strains A–E, with CTX-M-15 β-lactamase, all belong to the international O25:H4-ST131 clone
Siu Ha Lau,Mary E. Kaufmann,David M. Livermore,Neil Woodford,Geraldine A. Willshaw,Tom Cheasty,Katie Stamper,Suganya Reddy,John Cheesbrough,F. J. Bolton,Andrew J. Fox,Mathew Upton +11 more
TL;DR: The future spread of the ST131 clone, and its UK variants, should be monitored closely and the pathogenic mechanisms explaining their success should be investigated.
Journal ArticleDOI
Rapid identification of uropathogenic Escherichia coli of the O25:H4-ST131 clonal lineage using the DiversiLab repetitive sequence-based PCR system
Siu Ha Lau,J. Cheesborough,Mary E. Kaufmann,Neil Woodford,A.R. Dodgson,K.J. Dodgson,E.J. Bolton,Andrew J. Fox,Mathew Upton +8 more
TL;DR: It is suggested that introduction of the DiversiLab system would be useful for rapid exclusion of E. coli isolates during outbreak investigations, and that the approach could be employed for surveillance for pathogenic or antibiotic-resistant clones of this organism.