Soaira Mendoza

TL;DR: Metformin decreases Izero in hyperinsulinemic PCOS patients, reverses the hyperinsulinemia-driven endocrinopathy, decreases PAI-1, and decreases Lp(a), and should thus reduce the increased risk of atherothrombosis in PCOS.

TL;DR: An expanded postprandial hypertriglyceridemia in PCOS women is related to a higher waist-to-hip ratio and insulin resistance, regardless of obesity, and contributes to increase the risk for coronary artery disease.

TL;DR: Selective alteration of PR-T GL and PI-TGL by estrogens and Oxandrolone may provide an approach to better understanding of the interaction of lipases and triglycerides in familial and acquired hypertriglyceridemia.

TL;DR: Within Venezuelan schools, private schoolchildren were heavier, taller, had marginally higher Quetelet indices, and had considerably higher fasting plasma cholesterol, plasma high-density lipo-protein (C-HDL), and plasma low-density lipid levels, compared to public Venezuelan schoolchildren, which suggest augmented risk for coronary heart disease in Venezuelans within this lipid-lipoprotein frame of reference.

TL;DR: Assessment of Venezuelan school children with cross-cultural comparisons to American school children from suburban Cincinnati, Ohio revealed 2 major, consistent differences; Venezuelan children had higher fasting plasma triglyceride and lower HDL-C levels, not attributable to systematic differences in Quetelet index, laboratory methodology, subject selection, or sampling technique.