S
Somayeh Salarinejad
Researcher at Tehran University of Medical Sciences
Publications - 9
Citations - 222
Somayeh Salarinejad is an academic researcher from Tehran University of Medical Sciences. The author has contributed to research in topics: Chemistry & Pyridazine. The author has an hindex of 3, co-authored 6 publications receiving 69 citations.
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Journal ArticleDOI
A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy.
Adileh Ayati,Setareh Moghimi,Somayeh Salarinejad,Maliheh Safavi,Behjat Pouramiri,Alireza Foroumadi +5 more
TL;DR: The recent advances on the discovery and development of different EGFR inhibitors and the use of various therapeutic strategies such as multi-targeting agents and combination therapies have also been reviewed.
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6-Cinnamoyl-4-arylaminothienopyrimidines as highly potent cytotoxic agents: Design, synthesis and structure-activity relationship studies.
Mahsa Toolabi,Setareh Moghimi,Tayebeh Oghabi Bakhshaiesh,Somayeh Salarinejad,Ayoub Aghcheli,Zaman Hasanvand,Elahe Nazeri,Ali Khalaj,Rezvan Esmaeili,Alireza Foroumadi +9 more
TL;DR: In silico pharmacokinetic prediction indicated the acceptable bioavailability of all final compounds and the results provided evidence that these compounds induced cell death via apoptosis and arrested cell growth in sub-G1 phase.
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Synthesis, in-vitro evaluation, molecular docking, and kinetic studies of pyridazine-triazole hybrid system as novel α-glucosidase inhibitors
Setareh Moghimi,Somayeh Salarinejad,Mahsa Toolabi,Loghman Firoozpour,Seyed Esmaeil Sadat Ebrahimi,Fatemeh Safari,Fatemeh Madani-Qamsari,Somayeh Mojtabavi,Mohammad Ali Faramarzi,Saeed Karima,Roya Pakrad,Alireza Foroumadi +11 more
TL;DR: Pyridazine based 1,2,3-triazole derivatives as inhibitors of α-glucosidase have been reported in this paper, showing significant inhibitory activities.
Journal ArticleDOI
Design and synthesis of novel pyridazine N-aryl acetamides: In-vitro evaluation of α-glucosidase inhibition, docking, and kinetic studies.
Setareh Moghimi,Mahsa Toolabi,Somayeh Salarinejad,Loghman Firoozpour,Seyed Esmaeil Sadat Ebrahimi,Fatemeh Safari,Somayeh Mojtabavi,Mohammad Ali Faramarzi,Alireza Foroumadi +8 more
TL;DR: By this approach, a new series of pyridazine-based compounds were synthesized, characterized and evaluated for their activities against α-glucosidase enzyme, establishing that twelve compounds are more potent than acarbose.
Journal ArticleDOI
Design, synthesis, molecular docking study, and antibacterial evaluation of some new fluoroquinolone analogues bearing a quinazolinone moiety
Maryam Norouzbahari,Somayeh Salarinejad,Mümtaz Güran,Gizem Şanlıtürk,Zahra Emamgholipour,Hamid Reza Bijanzadeh,Mahsa Toolabi,Alireza Foroumadi +7 more
TL;DR: The results of the current study demonstrated that the novel ciprofloxacin and sarafloxacIn derivatives synthesized here have promising antibacterial activities and have potential for wider antibacterial applications following further analysis.