S
Sonal N. Patel
Researcher at California Institute of Technology
Publications - 3
Citations - 85
Sonal N. Patel is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Fetus & Immunoglobulin A. The author has an hindex of 2, co-authored 3 publications receiving 82 citations.
Papers
More filters
Journal ArticleDOI
Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice.
Eun Mi Hur,Sonal N. Patel,Saki Shimizu,Dinesh S. Rao,Priyanthi N. P. Gnanapragasam,Dong Sung An,Lili Yang,David Baltimore +7 more
TL;DR: It is shown that the polymeric IgA form of anti-HIV antibody inhibits HIV mucosal transmission more effectively than the monomeric IgA or IgG1 form in a comparable range of concentrations in humanized mice.
Journal ArticleDOI
Maternal and fetal factors that contribute to the localization of T regulatory cells during pregnancy.
TL;DR: To determine the interplay between fetal antigenicity and local maternal factors in determining reproductive tract T regulatory (Treg) cell accumulation during pregnancy, data are presented on Treg cell accumulation inoters during pregnancy.
Journal ArticleDOI
Engineering Antibodies to Enhance Activity and Increase Half-life
Stuart A. Sievers,Sonal N. Patel,Kathleen Bennett,Florian Klein,Michel C. Nussenzweig,Pamela J. Bjorkman +5 more
TL;DR: This work has constructed several mutations in regions that have been predicted to have high aggregation propensities, and has tested them for polyreactivity and potency in neutralization assays, and initial results show that these novel reagents have reduced polyreactivily, yet they still maintain their potency in in vitro neutralization Assays.