Songyan Gao

TL;DR: FFJQC alleviated the CaOx-induced renal EMT and fibrosis by regulating TGF-β/smad pathway and is an important traditional Chinese medicine for the treatment of CaOx’sinduced renal injury and Fibrosis.

TL;DR: Wang et al. as mentioned in this paper investigated the protective effects of rhizoma coptidis (RCE) extracts against sepsis-associated acute kidney injury (SA-AKI) and explore the underlying mechanisms with metabolomics-based network pharmacology.

TL;DR: The EEOS can inhibit the stones formation by improving oxidative stress and inflammation mediated by glycerophospholipid metabolism, providing a new direction for further study of the efficacy of OS.

TL;DR: Wang et al. as mentioned in this paper conducted an integrated proteomic and metabolomic analysis coupled with a bioinformatic analysis using ingenuity pathway analysis (IPA) methods, and found that BDE-47 mainly affected the molecules involved in free radical scavenging, cell death and survival, neurological disease, and inflammatory response.

TL;DR: In this paper, an extraction method of a clerodendranthus spicatus total flavone extract is described, which comprises the following steps: adding an ethanol aqueous solution with a liquid-material ratio of 5-25 L/Kg and a concentration of 0-95% into a clericsnthus powder, performing soaking at room temperature for 1-48h with stirring, performing ultrasonic treatment, filtering the obtained extract liquid, and concentrating filtrate to obtain a paste; and separating the paste with weak-polar macroporous adsorbent