S
Sónia M. Cunha
Researcher at Erasmus University Rotterdam
Publications - 2
Citations - 170
Sónia M. Cunha is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Androgen receptor & Binding site. The author has an hindex of 2, co-authored 2 publications receiving 159 citations.
Papers
More filters
Journal ArticleDOI
Compartmentalization of androgen receptor protein–protein interactions in living cells
Martin E. van Royen,Sónia M. Cunha,Maartje C. Brink,Karin A. Mattern,Alex L. Nigg,Hendrikus J. Dubbink,Pernette J. Verschure,Jan Trapman,Adriaan B. Houtsmuller +8 more
TL;DR: Evidence is provided that AR N/C interactions occur predominantly when ARs are mobile, possibly to prevent unfavorable or untimely cofactor interactions and to maintain spatiotemporal organization of AR coregulators.
Journal ArticleDOI
A multi-parameter imaging assay identifies different stages of ligand-induced androgen receptor activation
Martin E. van Royen,Dennis J. van de Wijngaart,Sónia M. Cunha,Jan Trapman,Adriaan B. Houtsmuller +4 more
TL;DR: A sensitive assay that can be used to quantitatively assess the activity of agonistic and antagonistic AR ligands is presented and shows a strong correlation between the ligand‐induced AR N/C‐interaction and transcriptional activity in wild type AR, but also in AR mutants with broadened ligand responsiveness.