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Sonja Kössler
Researcher at University of Salzburg
Publications - 3
Citations - 112
Sonja Kössler is an academic researcher from University of Salzburg. The author has contributed to research in topics: Mutant & Mitochondrion. The author has an hindex of 3, co-authored 3 publications receiving 108 citations.
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The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
Gino Heeren,Mark Rinnerthaler,Peter Laun,Phyllis von Seyerl,Sonja Kössler,Harald Klinger,Stefanie Jarolim,Birgit Simon-Nobbe,M. Hager,Christoph Schüller,Didac Carmona-Gutierrez,Lore Breitenbach-Koller,Christoph Mück,Pidder Jansen-Dürr,Alfredo Criollo,Guido Kroemer,Frank Madeo,Michael Breitenbach +17 more
TL;DR: In this paper, the authors present a new long-lived yeast deletion mutation,afo1 (for aging factor one), that confers a 60% increase in replicative lifespan.
Journal ArticleDOI
Senescence and apoptosis in yeast mother cell-specific aging and in higher cells : A short review
Peter Laun,Gino Heeren,Mark Rinnerthaler,Raphaela Rid,Sonja Kössler,Lore Koller,Michael Breitenbach +6 more
TL;DR: The question whether apoptosis (or parts of the apoptotic process) are a possible cause of aging or vice versa is asked and the role of the cellular stress response system in both of these processes is investigated.
The mitochondrial ribosomal of the large subunit, afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
Gino Heeren,Mark Rinnerthaler,Peter Laun,P. von Seyerl,Sonja Kössler,Harald Klinger,M. Hager,E. Bogengruber,Stefanie Jarolim,Birgit Simon-Nobbe,Christoph Schüller,Didac Carmona-Gutierrez,Lore Breitenbach-Koller,Christoph Mück,Pidder Jansen-Dürr,Alfredo Criollo,Guido Kroemer,Frank Madeo,Michael Breitenbach +18 more
TL;DR: A new long-lived yeast deletion mutation,afo1 (for aging factor one), that confers a 60% increase in replicative lifespan and establishes a new connection between mitochondria, metabolism and aging.