S
Sophie Brasselet
Researcher at Aix-Marseille University
Publications - 229
Citations - 6361
Sophie Brasselet is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Second-harmonic generation & Microscopy. The author has an hindex of 43, co-authored 214 publications receiving 5714 citations. Previous affiliations of Sophie Brasselet include Centre national de la recherche scientifique & École centrale de Marseille.
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Journal ArticleDOI
Collagen reorganization in cartilage under strain probed by polarization sensitive second harmonic generation microscopy
TL;DR: P-SHG imaging is used to investigate osteoarthritic cartilage from total knee replacement surgery, and reveals widespread heterogeneity across samples both microscale fibril orientations and their sub-micron organization.
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Microscopic structural study of collagen aging in isolated fibrils using polarized second harmonic generation
Dora Aït-Belkacem,Marie Guilbert,Muriel Roche,Julien Duboisset,Patrick Ferrand,Ganesh D. Sockalingum,Pierre Jeannesson,Sophie Brasselet +7 more
TL;DR: Polarization resolved second harmonic generation images are analyzed using a generic approach of the molecular disorder information in collagen fibrils, revealing significant changes upon aging, with a direct correlation between molecular disorder and fibril diameters.
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Bright Luminescent Silica Nanoparticles for Two-Photon Microscopy Imaging via Controlled Formation of 4,4′-Diethylaminostyryl-2,2′-bipyridine Zn(II) Surface Complexes
Nuria Rendón,Adrien Bourdolle,Patrice L. Baldeck,Hubert Le Bozec,Chantal Andraud,Sophie Brasselet,Christophe Copéret,Christophe Copéret,Olivier Maury +8 more
TL;DR: In this paper, a two-photon absorbing (2P absorbing) surface was obtained by grafting on the surface silanols of a silica partially dehydroxylated at 700 °C followed by the coordination of DEAS-bipy.
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Relation between quantum and geometric dimensionalities in molecular nonlinear optics: beyond the two-level model for anisotropic systems
Sophie Brasselet,Joseph Zyss +1 more
TL;DR: In this article, the authors show that appropriate geometric (e.g., tensorial) considerations combined with an n-level quantum model (n≥3) are able to account for nonlinear optical susceptibilities of two- or three-dimensional molecular systems.
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Ultimate use of two-photon fluorescence microscopy to map orientational behavior of fluorophores.
Patrick Ferrand,Paulina Gasecka,Alla Kress,Xiao Wang,Fatma-Zohra Bioud,Julien Duboisset,Sophie Brasselet +6 more
TL;DR: This work shows that polarized two-photon fluorescence based on tunable linear dichroism allows for the retrieval of this distribution with reasonable fidelity and without invoking either an a priori knowledge of the system to be investigated or a geometrical model.