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Sophie Karcher
Researcher at University of Bordeaux
Publications - 13
Citations - 1649
Sophie Karcher is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Hazard ratio & Efavirenz. The author has an hindex of 7, co-authored 12 publications receiving 1398 citations. Previous affiliations of Sophie Karcher include French Institute of Health and Medical Research.
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Journal ArticleDOI
A Trial of Early Antiretrovirals and Isoniazid Preventive Therapy in Africa.
Christine Danel,Raoul Moh,Delphine Gabillard,Anani Badje,Le Carrou J,Ouassa T,Eric Ouattara,Anzian A,Jean-Baptiste Ntakpe,Albert Minga,Gérard-Menan Kouamé,Bouhoussou F,Emieme A,Abo Kouame,Inwoley A,Toni Td,Ahiboh H,Kabran M,Rabe C,Sidibé B,Nzunetu G,Konan R,Gnokoro J,Gouesse P,Messou E,Dohoun L,Kamagate S,Yao A,Amon S,Kouame Ab,Koua A,Kouamé E,Ndri Y,Ba-Gomis O,Daligou M,Ackoundzé S,Hawerlander D,Ani A,Dembélé F,Koné F,Guéhi C,Kanga C,Koule S,Séri J,Oyebi M,Mbakop N,Makaila O,Babatunde C,Babatounde N,Bleoué G,Tchoutedjem M,Kouadio Ac,Sena G,Yededji Sy,Assi R,Bakayoko A,Mahassadi A,Attia A,Oussou A,Mobio M,Bamba D,Koman M,Horo A,Nina Deschamps,Chenal H,Sassan-Morokro M,Konate S,Aka K,Aoussi E,Journot,Nchot C,Sophie Karcher,Chaix Ml,Christine Rouzioux,Sow Ps,Perronne C,Girard Pm,Menan H,Bissagnene E,Kadio A,Ettiegne-Traore,Moh-Semdé C,Massumbuko Jm,Chêne G,Dosso M,Domoua Sk,N'Dri-Yoman T,Roger Salamon,Serge-Paul Eholié,Xavier Anglaret +89 more
TL;DR: In this African country, immediate ART and 6 months of IPT independently led to lower rates of severe illness than did deferred ART and no IPT, both overall and among patients with CD4+ counts of at least 500 cells per cubic millimeter.
Journal ArticleDOI
Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants.
Siaka Toure,Bertin Kouadio,Catherine Seyler,Catherine Seyler,Moussa Traore,Nicole Dakoury-Dogbo,Julien Duvignac,Julien Duvignac,Nafissatou Diakite,Sophie Karcher,Sophie Karcher,Christophe Grundmann,Richard Marlink,François Dabis,François Dabis,Xavier Anglaret,Xavier Anglaret +16 more
TL;DR: In this rapidly scaling-up program of access to antiretroviral treatment in Côte d'Ivoire, survival and immune reconstitution were good; women and patients followed up in centers with longer experience had better outcomes; outcomes were similar in zidovudine/stavudine-based regimens and in efavirenz/nevirapine- based regimens.
Journal ArticleDOI
Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial
Collins Iwuji,Collins Iwuji,Joanna Orne-Gliemann,Joseph Larmarange,Eric Balestre,Rodolphe Thiébaut,Frank Tanser,Nonhlanhla Okesola,Thembisa Makowa,Jaco Dreyer,Kobus Herbst,Nuala McGrath,Nuala McGrath,Till Bärnighausen,Till Bärnighausen,Sylvie Boyer,Tulio de Oliveira,Claire Rekacewicz,Brigitte Bazin,Marie-Louise Newell,Deenan Pillay,François Dabis,Collins Iwuji,Kevi Naidu,Tamsen J. Rochat,Johannes Henning Viljoen,Thembelihle Zuma,Sophie Karcher,Melanie Plazy,Mélanie Prague,Thierry Tiendrebeogo,Hermann Donfouet,Andréa Gosset,Laura March,Camelia Protopopescu,Bruno Spire,Alexandra Calmy,Maxime Inghels,Hassimiou Diallo,Vincent Calvez,Anne Derache,Anne-Geneviève Marcelin,Rosemary Dray-Spira,Kamal El Farouki,Richard J Lessells,Kenneth A. Freedberg,John Imrie,Marie-Laure Chaix,Colin Newell,Jan A. C. Hontelez +49 more
TL;DR: In this paper, the effect of universal test and treat on HIV acquisition at population level in a high prevalence rural region of South Africa was investigated in a phase 4, open-label, cluster randomised trial of 22 communities in rural KwaZulu-Natal, South Africa.
Journal ArticleDOI
Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial
Anani Badje,Raoul Moh,Delphine Gabillard,Calixte Guéhi,Mathieu Kabran,Jean-Baptiste Ntakpe,Jérome Le Carrou,Gérard M Kouame,Eric Ouattara,Eugène Messou,Amani Anzian,Albert Minga,Joachim Gnokoro,Patrice Gouesse,Arlette Emieme,Thomas-d'Aquin Toni,Cyprien Rabe,Baba Sidibé,Gustave Nzunetu,Lambert Dohoun,Abo Yao,Synali Kamagate,Solange Amon,Amadou-Barenson Kouame,Aboli Koua,Emmanuel Kouamé,Marcelle Daligou,Denise Hawerlander,Simplice Ackoundzé,Serge Koule,Jonas Séri,Alex Ani,Fassery Dembélé,Fatoumata Koné,Mykayila Oyebi,Nathalie Mbakop,Oyewole Makaila,Carolle Babatunde,Nathaniel Babatunde,Gisèle Bleoué,Mireille Tchoutedjem,Alain-Claude Kouadio,Ghislaine Sena,Sahinou-Yediga Yededji,Sophie Karcher,Christine Rouzioux,Abo Kouame,Rodrigue Assi,Alima Bakayoko,Serge K Domoua,Nina Deschamps,Kakou Aka,Thérèse N'Dri-Yoman,Roger Salamon,Valérie Journot,Hughes Ahibo,Timothée Ouassa,Hervé Menan,André Inwoley,Christine Danel,Serge Eholié,Xavier Anglaret,Gérard-Menan Kouamé,Yao Abo,Serge-K. Domoua,Ben-Ahoussi Ndja,Blandine Adou,Constance Kanga,Eba Aoussi,Emmanuel Bissagnene,Olivier Ba-Gomis,Yves-Alain Zike,Claude Akakpo,Madeleine Sassan-Morokro,Max Mobio,Bamba Doféré,Koman Mesmin,Alain Attia,Alassane Mahassadi,Apollinaire Horo,Armel Oussou,Marie-Laure Chaix,Gilles Peytavin,Mariatou Koné,Kouamé N'Guessan,Raïmi Fassassi,Serge Niangoran,Annabel Desgrées-du-Loû,Rosemary Dray Spira,Kévin Jean,Romuald Konan,Franck Bohoussou,Cyril Yao-Yapi,Larissa N'guessan-Koffi,Bertine Siloué,Adoulaye Cissé,Adrienne Aboua,Sylvie Konan,Antoine Kouamé,Celestin N'Chot,Elvis Amani,Gwenaëlle Clouet,Bruno Debono,Geneviève Chêne,Mireille Dosso,Pierre-Marie Girard,Vincent Jarlier,Jean-Marie Masumbuko,Christian Perronne,Papa-Salif Sow,Serge-Paul Eholié +110 more
TL;DR: 6 months of IPT has a durable protective effect in reducing mortality in HIV-infected people, even in people with high CD4 cell counts and who have started ART.
Journal ArticleDOI
Antiretroviral treatment changes in adults from Côte d'Ivoire: the roles of tuberculosis and pregnancy.
Eugène Messou,Xavier Anglaret,Julien Duvignac,Eric Konan-N'Dri,Eric Komena,Joachim Gnokoro,Sophie Karcher,Anthony Tanoh,Thérèse N'Dri-Yoman,Catherine Seyler +9 more
TL;DR: During the first months following antiretroviral treatment initiation, a third of all treatment changes occurred for reasons other than intolerance to the drug or treatment failure, indicating drug forecasting is crucial to ensuring the success of HIV treatment programmes.