Soter Dai

TL;DR: The findings substantiate the idea that stress-induced glandular ulcers result from vagal-mediated increased gastric contractions.

TL;DR: It is concluded that rats with experimentally induced rumenal ulcers may be a more logical model for assessing the activity of anti-ulcer agents in preventing peptic ulceration associated with accumulation of gastric acid.

TL;DR: The effects of 10-day pretreatment with i.p. injections of zinc chloride significantly reduced the volume of gastric secretion and the total acid output as well as the incidence of Gastric ulcers induced either by stress or by acid accumulation support the idea zinc compounds may be useful in the treatment of gastrics ulcers.

TL;DR: Observations provide added support for the hypothesis that stress induces vagal overactivity, probably of central origin, and are probably responsible for degeneration of the mucosal cells leading to the formation of stress-induced ulcers in the rat.

TL;DR: The results obtained with metiamide indicate that histamine plays a role in basal gastric secretion and in the pathogenesis of stress ulcers and it is suggested that H2 receptors may also be involved in gastric motility.