S
Srinivas V. Koduru
Researcher at Pennsylvania State University
Publications - 45
Citations - 2330
Srinivas V. Koduru is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Solanum aculeastrum & microRNA. The author has an hindex of 23, co-authored 42 publications receiving 1849 citations. Previous affiliations of Srinivas V. Koduru include University of Kentucky & University of Fort Hare.
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A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer.
Amon Asgharpour,Sophie C. Cazanave,Tommy Pacana,Mulugeta Seneshaw,Robert Vincent,Bubu A. Banini,Divya P. Kumar,Kalyani Daita,Hae Ki Min,Faridoddin Mirshahi,Pierre Bedossa,Xiaochen Sun,Yujin Hoshida,Srinivas V. Koduru,Daniel Contaifer,Urszula Osinska Warncke,Dayanjan S. Wijesinghe,Arun J. Sanyal +17 more
TL;DR: A diet-induced animal model of non-alcoholic fatty liver disease (DIAMOND) that recapitulates the key physiological, metabolic, histologic, transcriptomic and cell-signaling changes seen in humans with progressive NASH is described.
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Notch-1 Inhibition by Withaferin-A: A Therapeutic Target against Colon Carcinogenesis
TL;DR: Withaferin-A (WA) is a bioactive compound derived from Withania somnifera, which inhibits Notch-1 signaling and downregulates prosurvival pathways, such as Akt/NF-κB/Bcl-2, in three colon cancer cell lines.
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Antibacterial and antioxidant properties of the methanol extracts of the leaves and stems of Calpurnia aurea
TL;DR: The results from this study indicate that the leaves and stem extracts of Calpurnia aurea possess antioxidant properties and could serve as free radical inhibitors or scavenger or, acting possibly as primary antioxidants.
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Antimicrobial activity of Solanum aculeastrum
TL;DR: The fruit and leaf extracts of this plant were investigated for in vitro antimicrobial activity against 10 selected bacterial and 5 fungal strains and the most resistant organisms were Aspergillus niger, Candida albicans.
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Diosgenin targets Akt‐mediated prosurvival signaling in human breast cancer cells
Sowmyalakshmi Srinivasan,Srinivas V. Koduru,Raj Kumar,Guhan Venguswamy,Natasha Kyprianou,Chendil Damodaran +5 more
TL;DR: It is suggested that diosgenin might prove to be a potential chemotherapeutic agent for the treatment of BCa because of its ability to inhibit Akt signaling.