S
Srinivasagam Rajasankar
Researcher at Annamalai University
Publications - 13
Citations - 569
Srinivasagam Rajasankar is an academic researcher from Annamalai University. The author has contributed to research in topics: Rotenone & Neuroprotection. The author has an hindex of 9, co-authored 13 publications receiving 491 citations.
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Journal ArticleDOI
Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse.
Srinivasagam Rajasankar,Thamilarasan Manivasagam,Venkatachalam Sankar,Seppan Prakash,R. Muthusamy,Arumugam Krishnamurti,Sankar Surendran +6 more
TL;DR: The data suggest that Ws is a potential drug in treating catecholamines, oxidative damage and physiological abnormalities seen in the PD mouse.
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Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease.
TL;DR: Data suggests that A-Extract is a potential drug in treating oxidative damage and physiological abnormalities seen in the PD mouse, if documented also in patients with PD.
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Parkinson’s disease: oxidative stress and therapeutic approaches
TL;DR: Recent studies suggest that herbal medicines can improve molecular changes and motor functions seen in PD.
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Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells
Muthu Ramkumar,Srinivasagam Rajasankar,Veerappan Venkatesh Gobi,Chinnasamy Dhanalakshmi,Thamilarasan Manivasagam,Arokiasamy Justin Thenmozhi,Musthafa Mohamed Essa,Musthafa Mohamed Essa,Ameer Kalandar,Ranganathan Chidambaram +9 more
TL;DR: The results of the present study indicated that the DMC may serve as a potent therapeutic agent particularly for the treatment of neurodegenerative diseases like PD, further pre-clinical and clinical studies are required.
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Resveratrol attenuates oxidative stress and improves behaviour in 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) challenged mice.
Annadurai Anandhan,Kuppusamy Tamilselvam,Dhanraj Vijayraja,Nataraj Ashokkumar,Srinivasagam Rajasankar,Thamilarasan Manivasagam +5 more
TL;DR: Pretreatment of resveratrol significantly reversed toxic effects of MPTP by increasing the levels of dopamine, its metabolites, GSH and activities of GPx and reducing levels of TBARS, catalase and SOD activities along with enhanced behavior performance.