S
Sriram Ravindran
Researcher at University of Illinois at Chicago
Publications - 67
Citations - 2373
Sriram Ravindran is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Mesenchymal stem cell & Extracellular matrix. The author has an hindex of 22, co-authored 55 publications receiving 1510 citations.
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Journal ArticleDOI
Nano-scale modification of titanium implant surfaces to enhance osseointegration
Júlio C.M. Souza,Mariane Beatriz Sordi,Miya Kanazawa,Sriram Ravindran,Bruno Henriques,Filipe Samuel Silva,Conrado Aparicio,Lyndon F. Cooper +7 more
TL;DR: An improvement in wettability and bioactivity of titanium implant surfaces has been accomplished by combining micro and nano-scale modification and functionalization with protein, peptides, and bioactive compounds.
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Exosomes as biomimetic tools for stem cell differentiation: Applications in dental pulp tissue regeneration
TL;DR: The results indicate that exosomes isolated under odontogenic conditions are better inducers of stem cell differentiation and tissue regeneration and show the importance of considering the source and state of exosome donor cells before a choice is made for therapeutic applications.
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Hijacking the Cellular Mail: Exosome Mediated Differentiation of Mesenchymal Stem Cells
TL;DR: The results indicate that proosteogenic exosomes isolated from cell cultures can induce lineage specific differentiation of naïve MSCs in vitro and in vivo and opens up new avenues for future research.
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Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion.
Biji Mathew,Sriram Ravindran,Xiaorong Liu,Leianne Torres,Mohansrinivas Chennakesavalu,Chun-Chieh Huang,Liang Feng,Ruth Zelka,Jasmine Lopez,Monica Sharma,Steven Roth +10 more
TL;DR: The administration of MSC-EVs into the vitreous humor 24 h after retinal ischemia in a rat model significantly enhanced functional recovery, and decreased neuro-inflammation and apoptosis, highlighting the potential of M SC-EV as biomaterials for neuroprotective and regenerative therapy in retinal disorders.
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Functionally engineered extracellular vesicles improve bone regeneration.
Chun-Chieh Huang,Miya Kang,Yu Lu,Sajjad Shirazi,Jose Iriarte Diaz,Lyndon F. Cooper,Praveen Gajendrareddy,Sriram Ravindran +7 more
TL;DR: EV' functionality may be engineered by genetic modification of the parental MSCs to induce osteoinduction and bone regeneration, indicating alternative approaches to enhancing bone regeneration.