S
SS Jayasinghe
Researcher at University of Ruhuna
Publications - 27
Citations - 853
SS Jayasinghe is an academic researcher from University of Ruhuna. The author has contributed to research in topics: Insulin resistance & Pioglitazone. The author has an hindex of 8, co-authored 25 publications receiving 598 citations. Previous affiliations of SS Jayasinghe include University of Peradeniya.
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Journal ArticleDOI
Arsenic and human health effects: A review.
Khaja Shameem Mohammed Abdul,SS Jayasinghe,E. P. S. Chandana,Channa Jayasumana,P. Mangala C.S. De Silva +4 more
TL;DR: The effects of arsenic on the human body with a main focus on assorted organ systems with respective disease conditions are outlined and underlying mechanisms of disease development in each organ system due to arsenic have been explored.
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Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka.
Pallagae Mangala C. S. De Silva,Khaja Shameem Mohammed Abdul,Eakanayake M. D. V. Eakanayake,SS Jayasinghe,Channa Jayasumana,H.B. Asanthi,Hettiarachigae S. D. Perera,Gamage G. Tushara Chaminda,E. P. S. Chandana,Sisira Siribaddana +9 more
TL;DR: Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2, which may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary Kim-1and NGAL in early detection of renal injury among farming communities in Southern Sri Lanka.
Comparison of insulin resistance by indirect methods - HOMA, QUICKI and McAuley - with fasting insulin in patients with type 2 diabetes in Galle, Sri Lanka: A pilot study
LM Hettihewa,Shalika Palangasinghe,SS Jayasinghe,Sudari W Gunasekara,Thilak Priyantha Weerarathna +4 more
TL;DR: FI measurement alone in diabetic patients has detected IR in 81% of patients, similar to the other standard methods (McA, HOMA and QUICKI; 93%).
Journal ArticleDOI
Simple and sensitive liquid chromatography–tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies
Klintean Wunnapuk,Gregory Medley,Xin Liu,Jeffrey E. Grice,SS Jayasinghe,SS Jayasinghe,Indika Gawarammana,Indika Gawarammana,Nicholas A. Buckley,Nicholas A. Buckley,Nicholas A. Buckley,Michael S. Roberts,Michael S. Roberts +12 more
TL;DR: PQ in plasma and urine samples was stable when stored at -70 °C for three freeze-thaw cycles and applied to determine PQ concentration in rat and human samples.
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Effects of Acute Organophosphorus Poisoning on Function of Peripheral Nerves: A Cohort Study
TL;DR: There was no strong evidence of irreversible peripheral nerve damage following acute OP poisoning, however further studies are required.