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Staffan Johansson

Researcher at Uppsala University

Publications -  93
Citations -  4300

Staffan Johansson is an academic researcher from Uppsala University. The author has contributed to research in topics: Integrin & Fibronectin. The author has an hindex of 35, co-authored 88 publications receiving 3992 citations. Previous affiliations of Staffan Johansson include Swedish University of Agricultural Sciences & University of Gothenburg.

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Fibronectin-integrin interactions.

TL;DR: Three areas related to fibronectin and its receptors which have developed rapidly during the last few years are summarized in this review: the mechanisms of interactions between fibronctin and integrins, fibronECTin polymerization, and in vivo functions of the proteins as studied by gene targeting in mice.
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Beta 1 integrin-dependent and -independent polymerization of fibronectin.

TL;DR: While both alpha 5 beta 1A and alpha vbeta 3 are able to support adhesion to fibronectin, alpha v beta 3 dominates in the formation of focal contacts, and alpha 5beta 1A has a prime function in fibronECTin matrix assembly.
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Stabilin-1 and −2 constitute a novel family of fasciclin-like hyaluronan receptor homologues

TL;DR: Stabilin-1 and stabilin-2 define a novel family of fasciclin-like hyaluronan receptor homologues that might play a role in cell—cell and cell—matrix interactions in vascular function and inflammatory processes.
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Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectin-binding MSCRAMMs and host cell beta1 integrins.

TL;DR: A model of S. aureus invasion is put forward in which host FN forms a bridge between the bacterial Fnbps and host cell beta1 integrins, leading to bacterial uptake.
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Amphibian neural crest cell migration on purified extracellular matrix components: a chondroitin sulfate proteoglycan inhibits locomotion on fibronectin substrates.

TL;DR: The results indicate that NC cell migration on FN involves two separate domains of the molecule, and that ChSP can modulate the migratory behavior ofNC cells moving along FN-rich pathways and may therefore influence directionally and subsequent localization of NC cells in the embryo.