S
Steen B. Pedersen
Researcher at Aarhus University Hospital
Publications - 255
Citations - 13944
Steen B. Pedersen is an academic researcher from Aarhus University Hospital. The author has contributed to research in topics: Adipose tissue & Insulin. The author has an hindex of 60, co-authored 241 publications receiving 12613 citations. Previous affiliations of Steen B. Pedersen include Mayo Clinic & Aarhus University.
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Journal ArticleDOI
Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.
Jens M. Bruun,Aina S. Lihn,Camilla Verdich,Steen B. Pedersen,Søren Toubro,Arne Astrup,Bjørn Richelsen +6 more
TL;DR: The inverse relationship between plasma adip onectin and cytokines in vivo and the cytokine-induced reduction in adiponectin mRNA in vitro suggests that endogenous cytokines may inhibit adiponECTin.
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Adiponectin: action, regulation and association to insulin sensitivity
TL;DR: Adiponectin in addition to possible anti‐inflammatory and anti‐atherogenic effects appears to be an insulin enhancer, with potential as a new pharmacologic treatment modality of the metabolic syndrome and type 2 diabetes.
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Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.
TL;DR: MCP-1 is correlated with specific macrophage markers, adiposity, and AT localization, but the relationship seems to be related to the number of AT-resident macrophages, which suggests that these antidiabetic compounds have antiinflammatory properties improving the low-grade inflammatory state observed in obesity.
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Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study
Maria Maersk,Anita Belza,Hans Stødkilde-Jørgensen,Steffen Ringgaard,Elizaveta Chabanova,Henrik S. Thomsen,Steen B. Pedersen,Arne Astrup,Bjørn Richelsen +8 more
TL;DR: Daily intake of SSSDs for 6 mo increases ectopic fat accumulation and lipids compared with milk, diet cola, and water, and is likely to enhance the risk of cardiovascular and metabolic diseases.
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High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition
Morten Poulsen,P. Vestergaard,Berthil F. Clasen,Yulia Radko,Lars Porskjær Christensen,Hans Stødkilde-Jørgensen,Niels Møller,Niels Jessen,Steen B. Pedersen,Jens Otto Lunde Jørgensen +9 more
TL;DR: The lack of effect disagrees with persuasive data obtained from rodent models and raises doubt about the justification of resveratrol as a human nutritional supplement in metabolic disorders.