Stefan Bleuler

TL;DR: Genevestigator V3 is a novel meta-analysis system resulting from new algorithmic and software development using a client/server architecture, large-scale manual curation and quality control of microarray data for several organisms, and curation of pathway data for mouse and Arabidopsis.

TL;DR: A methodology for comparing and validating biclustering methods that includes a simple binary reference model that captures the essential features of most bic Lustering approaches and proposes a fast divide-and-conquer algorithm (Bimax).

TL;DR: This work states that evolutionary multiobjective optimization has become established as a separate subdiscipline combining the fields of evolutionary computation and classical multiple criteria decision making.

TL;DR: In this article, the problem representation together with the variation operators is seen as an integral part of the optimization problem and can hence be easily separated from the selection operators, which makes it possible to specify and implement representation-independent selection modules, which form the essence of modern multiobjective optimization algorithms.

TL;DR: A novel graphical Gaussian modeling approach for reverse engineering of genetic regulatory networks with many genes and few observations is presented and modules of closely connected genes and candidate genes for possible cross-talk between the isoprenoid pathways are detected.