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Stefan Catsicas

Researcher at École Polytechnique Fédérale de Lausanne

Publications -  52
Citations -  5901

Stefan Catsicas is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Neurite & Synaptic vesicle. The author has an hindex of 30, co-authored 52 publications receiving 5682 citations. Previous affiliations of Stefan Catsicas include University of Lausanne & École Polytechnique.

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Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

TL;DR: Transgenic mice are generated in which neurons overexpress the human BCL-2 protein under the control of the neuron-specific enolase (NSE) or phosphoglycerate kinase (PGK) promoters to gain insight into the possible role of bcl-2 during NOCD in vivo.
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Cellular Toxicity of Carbon-Based Nanomaterials

TL;DR: This work clearly indicated that carbon-based nanomaterials are toxic while the hazardous effect is size-dependent, and cytotoxicity is enhanced when the surface of the particles is functionalized after an acid treatment.
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Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo

TL;DR: It is reported here that SNAP-25 is expressed in axonal growth cones during late stages of elongation and that selective inhibition of SNAP- 25 expression prevents neurite elongation by rat cortical neurons and PC-12 cells in vitro and by amacrine cells of the developing chick retina in vivo.
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Nanomechanics of microtubules.

TL;DR: The mechanical anisotropy of a single microtubules is determined by simultaneously measuring the Young's and the shear moduli in vitro by elastically deforming the microtubule deposited on a substrate tailored by electron-beam lithography with a tip of an atomic force microscope.
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SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

TL;DR: A role for SNAP-25 in fusion of dense core secretory granules with the plasma membrane in an endocrine cell type- the pancreatic B cell is suggested.