Stefan E. Pambuccian

TL;DR: G glycerol monolaurate—a widely used antimicrobial compound with inhibitory activity against the production of MIP-3α and other proinflammatory cytokines—can inhibit mucosal signalling and the innate and inflammatory response to HIV-1 and SIV in vitro, and in vivo it can protect rhesus macaques from acute infection despite repeated intra-vaginal exposure to high doses of SIV.

TL;DR: Of particular interest was the association of a gene expression signature enriched for genes involved in tumor invasion and metastasis with patients experiencing locally recurrent disease, suggesting that modulation of tumor-specific immune responses may play a role in local treatment failure in HNSCC.

TL;DR: It is demonstrated that computer-aided methods to classify image areas of interest and quantify IHC staining intensity within those areas can produce highly similar data to visual evaluation by a pathologist.

TL;DR: In this article, the gene expression of 20 ovarian carcinomas, 17 ovarian carcinoma metastatic to the omentum, and 50 normal ovaries was determined by Gene Logic Inc. using Affymetrix GeneChip HU_95 arrays containing ∼12,000 known genes.

TL;DR: Interactions between the alpha 5 beta 1-integrin and fibronectin mediate the formation of ovarian carcinoma spheroids and that their adhesion to extracellular matrix proteins at sites of secondary tumor growth may be mediated by a complex interaction between multiple integrins and their ligands.