S
Stefan Evers
Researcher at Hoffmann-La Roche
Publications - 41
Citations - 2542
Stefan Evers is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Proteome & Fibroblast activation protein, alpha. The author has an hindex of 16, co-authored 41 publications receiving 2129 citations.
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Journal ArticleDOI
The Where, the When, and the How of Immune Monitoring for Cancer Immunotherapies in the Era of Checkpoint Inhibition.
TL;DR: The concept of the tumor immunity continuum is proposed as a framework for developing rational combination strategies for anticancer immune therapies based on current understanding of tumor and circulating pharmacodynamic correlates of immune modulation.
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Mannose receptor-mediated regulation of serum glycoprotein homeostasis.
Sena J. Lee,Stefan Evers,Daniel Roeder,Albert F. Parlow,Juha Risteli,Leila Risteli,Y. C. Lee,Ten Feizi,Hanno Langen,Michel C. Nussenzweig,Michel C. Nussenzweig +10 more
TL;DR: MR appears to operate as an essential regulator of serum glycoprotein homeostasis by up-regulated during inflammation and wound healing.
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Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.
Christian Klein,Inja Waldhauer,Nicolini Valeria G,Anne Freimoser-Grundschober,Tapan K. Nayak,Danielle J. Vugts,Claire Dunn,Marije Bolijn,Jörg Benz,Martine Stihle,Sabine Lang,Michaele Roemmele,Hofer Thomas U,Erwin van Puijenbroek,David Wittig,Samuel Moser,Oliver Ast,Peter Brünker,Ingo H. Gorr,Sebastian Neumann,Maria Cristina De Vera Mudry,Heather Hinton,Flavio Crameri,Jose Saro,Stefan Evers,Christian Gerdes,Marina Bacac,Guus A.M.S. van Dongen,Ekkehard Moessner,Pablo Umana +29 more
TL;DR: Preclinical data support the ongoing clinical investigation of the cergutuzumab amunaleukin immunocytokine with abolished CD25 binding for the treatment of CEA-positive solid tumors in combination with PD-L1 checkpoint blockade and ADCC competent antibodies.
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Gene Expression Changes Triggered by Exposure of Haemophilus influenzae to Novobiocin or Ciprofloxacin: Combined Transcription and Translation Analysis
TL;DR: Treatment with the ATPase inhibitor Novobiocin changed the expression rates of many genes, reflecting the fact that the initiation of transcription for many genes is sensitive to DNA supercoiling.
Journal ArticleDOI
Two-dimensional map of the proteome of Haemophilus influenzae.
Hanno Langen,Bela Takacs,Stefan Evers,Peter Berndt,Hans-Werner Lahm,Beat Wipf,Christopher Gray,Michael Fountoulakis +7 more
TL;DR: A two‐dimensional database of the proteome of Haemophilus influenzae, a bacterium of medical interest of which the complete genome has been sequenced, is constructed, at present one of the largest two-dimensional proteome databases.