S
Stefanie Geisler
Researcher at Washington University in St. Louis
Publications - 32
Citations - 3084
Stefanie Geisler is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Ventral tegmental area & Rostromedial tegmental nucleus. The author has an hindex of 22, co-authored 28 publications receiving 2692 citations. Previous affiliations of Stefanie Geisler include Charité & University of Washington.
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Glutamatergic Afferents of the Ventral Tegmental Area in the Rat
TL;DR: This work found glutamatergic neurons innervating the VTA in almost all structures projecting there and that a majority of these are subcortical and VGLUT2 mRNA positive.
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The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta
TL;DR: Dense μ‐opioid receptor and somatostatin immunoreactivity characterize the RMTg, as do neurons projecting to the VTA/SNC that are enriched in GAD67 mRNA.
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Afferents of the ventral tegmental area in the rat‐anatomical substratum for integrative functions
Stefanie Geisler,Daniel S. Zahm +1 more
TL;DR: Injections of the anterograde tracers Phaseolus vulgaris‐leucoagglutinin or biotinylated dextran amine into selected forebrain structures revealed a surprisingly sparse terminal arborization in the VTA, indicating an anatomical network.
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Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.
TL;DR: SARM1 is established as the central determinant of a fundamental axonal degeneration pathway that is activated by diverse insults and it is suggested that targeting SARM1 or its downstream effectors may be a viable therapeutic option to prevent vincristine-induced peripheral polyneuropathy and possibly other peripheralpolyneuropathies.
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Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain
TL;DR: It is shown, using in situ hybridization and immunocytochemical double labeling at the light and electron microscopic level, that GABAergic neurons are scarce in the LHB and that glutamatergic axons from the LHb mostly target GABAergic neuron in the VTA and the mesopontine rostromedial tegmental nucleus (RMTg), also known as tail of the Vta (tVTA).