Stephen J Milan

TL;DR: Antibiotic therapy was shown to be effective at eradicating bacterial vaginosis during pregnancy, and treatment before 20 weeks' gestation did not reduce the risk of PTB less than 37 weeks, however these represent relatively small differences in the clinical setting.

TL;DR: An updated review of NICE guidance recommends omalizumab for use as add-on therapy in adults and children over six years of age with inadequately controlled severe persistent allergic IgE-mediated asthma who require continuous or frequent treatment with oral corticosteroids and a main focus of the updated review is subcutaneous administration, as this route is currently used in clinical practice.

TL;DR: To compare the effects of therapies targeting IL-5 signalling with placebo on exacerbations, health-related qualify of life (HRQoL) measures, and lung function in adults and children with chronic asthma, a first update of a previously published review in The Cochrane Library is published.

TL;DR: All three combined treatments led to statistically significant improvement in health status measurements, although the mean differences observed are relatively small in relation to the minimum clinically important difference.

TL;DR: Inhaled steroids reduced admission rates in patients with acute asthma, but it is unclear if there is a benefit of ICS when used in addition to systemic corticosteroids.