S
Stephen K. Cope
Researcher at University of North Carolina at Charlotte
Publications - 7
Citations - 424
Stephen K. Cope is an academic researcher from University of North Carolina at Charlotte. The author has contributed to research in topics: Gilman reagent & Reagent. The author has an hindex of 6, co-authored 7 publications receiving 410 citations.
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Journal ArticleDOI
Rapid injection NMR in mechanistic organocopper chemistry. Preparation of the elusive copper(III) intermediate.
TL;DR: The first example of this elusive species under conditions where it is stable for extended periods of time is prepared using rapid injection NMR (RI-NMR), establishing its structure and include two-bond 13C−13C coupling constants 2J across copper, measured on 13C-labeled material.
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Preparation of sigma- and pi-allylcopper(III) intermediates in SN2 and SN2' reactions of organocuprate(I) reagents with allylic substrates.
TL;DR: The exclusive formation of cis-cyano sigma-allyl CuIII intermediates in both the 1,4-addition of B to alpha-enones and its SN2alpha reaction with allylic substrates now makes sense in terms of pi-ally l intermediates, thus unifying the mechanisms of these two kinds of conjugate addition.
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Organocuprate Cross‐Coupling: The Central Role of the Copper(III) Intermediate and the Importance of the Copper(I) Precursor
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Neutral organocopper(III) complexes
Erika R. Bartholomew,Steven H. Bertz,Stephen K. Cope,Donna C. Dorton,Michael D. Murphy,Craig A. Ogle +5 more
TL;DR: Neutral organocopper(III) complexes have been prepared from organocuprate(I) reagents and alkyl halides in the presence of certain strongly electron donating ligands.
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Serendipity strikes again—efficient preparation of lithium tetramethylcuprate(III) via rapid injection NMR
Erika R. Bartholomew,Steven H. Bertz,Stephen K. Cope,Michael D. Murphy,Craig A. Ogle,Andy A. Thomas +5 more
TL;DR: Lithium tetramethylcuprate(III), Me(4)CuLi, the Cu(III) analog of the Gilman reagent, has been prepared in high yield from halo-Gilman reagents Me(2)Cu Li and found to have surprising thermal stability.