S
Stephen R. Pearce
Researcher at University of Sussex
Publications - 42
Citations - 4728
Stephen R. Pearce is an academic researcher from University of Sussex. The author has contributed to research in topics: Retrotransposon & Genome. The author has an hindex of 28, co-authored 42 publications receiving 4618 citations. Previous affiliations of Stephen R. Pearce include Scottish Crop Research Institute & Scripps Health.
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Journal ArticleDOI
Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport.
Stephen C. Hyde,Paul Emsley,Michael J. Hartshorn,Michael M. Mimmack,Uzi Gileadi,Stephen R. Pearce,Stephen R. Pearce,Maurice P. Gallagher,Maurice P. Gallagher,Deborah R. Gill,Roderick E. Hubbard,Christopher F. Higgins +11 more
TL;DR: A tertiary structure model of the ATP-binding cassettes characteristic of this class of transport system is presented, based on similarities between the predicted secondary structures of members of this family and the previously determined structure of adenylate kinase.
Journal ArticleDOI
Genetic distribution of Bare-1-like retrotransposable elements in the barley genome revealed by sequence-specific amplification polymorphisms (S-SAP)
Robbie Waugh,Karen McLean,Andrew J. Flavell,Stephen R. Pearce,Amar Kumar,Bill Thomas,Wayne Powell +6 more
TL;DR: A polymerase chain reaction (PCR)-based method which exploits this polymorphism for the generation of molecular markers in barley, which produces amplified fragments containing a Bare–1-like retrotransposon long terminal repeat (LTR) sequence at one end and a flanking host restriction site at the other.
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The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation.
TL;DR: It is postulate that the accumulation of such peptides may play a signaling role in the initiation of sporulation, and that the sporulation defect in opp mutants results from an inability to transport these peptides.
Journal ArticleDOI
Ty1-copia group retrotransposons are ubiquitous and heterogeneous in higher plants.
Andrew J. Flavell,Elizabeth Dunbar,Raymond Anderson,Stephen R. Pearce,Richard Hartley,Amar Kumar +5 more
TL;DR: Phylogenetic analysis of sequences shows that the degree of sequence divergence in the retrotransposon populations between any pair of species is proportional to the evolutionary distance between those species, which implies that sequence divergence during vertical transmission of Ty1-copia group retro Transposons within plant lineages has been a major factor in the evolution ofTy1-Copia group Retrotransposons in higher plants.
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Retrotransposon-based insertion polymorphisms (RBIP) for high throughput marker analysis.
TL;DR: Two assays based upon PCR detection of a polymorphic PDR1 retrotransposon insertion in Pisum sativum have been developed, which could in principle be applied to any transposable element in any plant species.