S
Steven C. March
Researcher at Johns Hopkins University School of Medicine
Publications - 4
Citations - 1860
Steven C. March is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Titration & In vitro. The author has an hindex of 4, co-authored 4 publications receiving 1857 citations.
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Journal ArticleDOI
A simplified method for cyanogen bromide activation of agarose for affinity chromatography
TL;DR: Agarose can be activated by adding cyanogen bromide, dissolved in acetonitrile, to beads suspended in a solution of sodium carbonate, and the necessity for manual titration and the use of a pH meter are eliminated.
Journal ArticleDOI
Macromolecular naloxone: A novel long-acting polymer-bound drug
TL;DR: A widely applicable, prolonged-action drug delivery system has been developed using naloxone, a pure narcotic antagonist, as a model, attached to an inert, water soluble polymer by reversible covalent bonds, whose slow cleavage releases active drug.
Book ChapterDOI
Affinity chromatography--old problems and new approaches.
TL;DR: The purification of macromolecules by biospecific adsorption-affinity chromatography is a technique with a long history although its application to a wide variety of problems is comparatively recent.
Journal ArticleDOI
Tritiation of endotoxin
TL;DR: Chromatographic analysis of the three tritiated endotoxins revealed that the biological activity associated with each labeled product appeared at the void volume, and in each case the Biological activity coincided with a peak in radioactivity.