Steven Roest

TL;DR: Preparing a shape‐adaptive, contact‐killing coating by tethering quaternary‐ammonium‐compounds onto hyperbranched polyurea coatings, able to kill adhering bacteria by partially enveloping them, which causes removal of membrane lipids and eventually lead to bacterial death.

TL;DR: Three out of five methods compared, including an established ASTM, are unsuitable for evaluating bacterial contact-killing surfaces and methods found suitable should be used in combination with a zone-of-inhibition-assay to establish absence of antimicrobial leaching, potentially interfering with contact- killing.

TL;DR: The low cytotoxicity of the micelles make them promising for drug delivery, and a method to synthesize AB(2) monomers, the corresponding hyperbranched and the corresponding amphiphilic hyper branched polymers in a one-pot procedure, starting from two commercial available compounds is reported.

TL;DR: Next-generation biomaterials should account for surface effects on phagocytosis in order to enhance the ability of these materials to resist biomaterial-associated-infection.

TL;DR: In this paper, the authors investigated the contribution of additional alkylation with methyl-iodide to the cationic-charge density of hexyl-bromide alkylated, hyperbranched polyurea-polyethyleneimine coatings.