S
Steven T. Charles
Researcher at University of Tennessee
Publications - 2
Citations - 296
Steven T. Charles is an academic researcher from University of Tennessee. The author has contributed to research in topics: Matrix metalloproteinase & Endothelial stem cell. The author has an hindex of 1, co-authored 2 publications receiving 288 citations.
Papers
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Journal ArticleDOI
Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro.
William J. Lamoreaux,Malinda E.C. Fitzgerald,Malinda E.C. Fitzgerald,Anton Reiner,Karen A. Hasty,Steven T. Charles +5 more
TL;DR: The data suggest that VEGF may modulate endothelial cell-derived MMP activity by increasing the abundance of gelatinase A; disinhibiting gelatinases A by decreasing the abundanceof TIMP-2; and disinhibititing preexisting collagenase by reducing levels of TIMP -1.
Book ChapterDOI
Diabetic Vitrectomy Update
TL;DR: It is essential to recognize that to a substantial extent, a diabetic patient requiring vitrectomy indicates a failure of the diabetic screening process, patient education, medical management, retinopathy screening, and/or laser treatment for diabetic Retinopathy.