Su Mei Cao

TL;DR: China is undergoing the cancer transition stage where the cancer spectrum is changing from developing country to developed country, with a rapidly increase cancer burden of colorectal, prostate, female breast cancers in addition to a high occurrence of infection-related and digestive cancers.

TL;DR: This review summarizes several large screening studies that have been conducted in the high-incidence areas of China for early detection of Nasopharyngeal carcinoma using anti–Epstein-Barr virus serum biomarkers.

TL;DR: NACT improved tumour control compared with CCRT alone in locoregionally advanced NPC, particularly at distant sites, however, there was no early gain in OS.

TL;DR: Smoking is not only associated with NPC risk in individuals from China but is also associated with EBV seropositivity in healthy males and is involved in EBV activation.

TL;DR: Elevated EBV antibodies, particularly with ascending titers, are strongly associated with an increased risk for NPC, with a striking dose-response relationship and most prominent during the first 5 years of follow-up.