S
Subhash P. Chavan
Researcher at Academy of Scientific and Innovative Research
Publications - 18
Citations - 60
Subhash P. Chavan is an academic researcher from Academy of Scientific and Innovative Research. The author has contributed to research in topics: Total synthesis & Enantioselective synthesis. The author has an hindex of 3, co-authored 18 publications receiving 31 citations. Previous affiliations of Subhash P. Chavan include National Chemical Laboratory.
Papers
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Journal ArticleDOI
Enantioselective Formal Total Synthesis of (-)-Quinagolide.
Subhash P. Chavan,Subhash P. Chavan,Appasaheb L. Kadam,Appasaheb L. Kadam,Rajesh G. Gonnade,Rajesh G. Gonnade +5 more
TL;DR: This is the first synthetic effort to access the core skeleton of (-)-quinagolide and an interesting reductive cleavage of the C-N bond in the electron-deficient isoquinuclidine skeleton under the Birch reduction conditions has been observed.
Journal ArticleDOI
Synthesis of 3-Azidopiperidine Skeleton Employing Ceric Ammonium Nitrate (CAN)-Mediated Regioselective Azidoalkoxylation of Enol Ether: Total Synthesis of D2 Receptor Agonist (±)-Quinagolide
Subhash P. Chavan,Subhash P. Chavan,Appasaheb L. Kadam,Appasaheb L. Kadam,Pradeep B. Lasonkar,Rajesh G. Gonnade,Rajesh G. Gonnade +6 more
TL;DR: The PPTS-catalyzed intramolecular diastereoselective Henry reaction to fix three contiguous stereocenters on tetrahydronaphthalene and the first-of-its-kind synthesis of the 3-azidopiperidine skeleton, using a CAN-mediated regioselectives azidoalkoxylation of enol ether, are important findings of the present work.
Journal ArticleDOI
Furan-Derived Chiral Bicycloaziridino Lactone Synthon: Collective Syntheses of Oseltamivir Phosphate (Tamiflu), (S)-Pipecolic acid and its 3-Hydroxy Derivatives.
Subhash P. Chavan,Subhash P. Chavan,Appasaheb L. Kadam,Appasaheb L. Kadam,Shrikrishna S. Shinde,Rajesh G. Gonnade,Rajesh G. Gonnade +6 more
TL;DR: The unified synthetic strategy for oseltamivir phosphate (tamiflu), ( S )-pipecolic acid and its 3-hydroxy derivatives from furan derived common chiral bicycloaziridino lactone synthon is described here.
Patent
Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds
Subhash P. Chavan,Amar Gopal Chittiboyina,Subhash K. Kamat,Uttam R. Kalkote,Thotapallil Ravindranathan +4 more
TL;DR: In this article, a novel route has been developed for substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol] compounds; crucial intermediates for D(+)-biotin of formula (7) which involves simple, efficient, practical and cost effective protocol.
Journal ArticleDOI
Multi-Step Synthesis of Miltefosine: Integration of Flow Chemistry with Continuous Mechanochemistry
Niteen B. Patil,Niteen B. Patil,Ranjit S. Atapalkar,Ranjit S. Atapalkar,Subhash P. Chavan,Subhash P. Chavan,Amol A. Kulkarni,Amol A. Kulkarni +7 more
TL;DR: In this paper, an advanced continuous flow synthesis of the blockbuster Leishmaniasis drug miltefosine from simple starting materials by a sequence involving four steps of chemical transformation including a continuous mechanochemical step was reported.