S
Sudin Bhattacharya
Researcher at Chittaranjan National Cancer Institute
Publications - 66
Citations - 1582
Sudin Bhattacharya is an academic researcher from Chittaranjan National Cancer Institute. The author has contributed to research in topics: Oxidative stress & Lipid peroxidation. The author has an hindex of 23, co-authored 64 publications receiving 1298 citations.
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Unveiling the groove binding mechanism of a biocompatible naphthalimide-based organoselenocyanate with calf thymus DNA: an "ex vivo" fluorescence imaging application appended by biophysical experiments and molecular docking simulations
Soumya Sundar Mati,Somnath Singha Roy,Sayantani Chall,Sudin Bhattacharya,Subhash Chandra Bhattacharya +4 more
TL;DR: Experimental results based on spectroscopy, isothermal calorimetry, electrochemistry aided with DNA-melting, and circular dichroism studies unambiguously established the formation of a groove binding network between the NPOS and ctDNA.
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Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation.
TL;DR: Indole-3-Carbinol has promising chemoprotective efficacy against DOX-induced toxicities and indicates its future use as an adjuvant in chemotherapy.
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Prevention of cadmium induced lipid peroxidation, depletion of some antioxidative enzymes and glutathione by a series of novel organoselenocyanates.
TL;DR: The study evidences the preventive effects of organoselenocyanates 4a-d against Cd induced lipid peroxidation and oxidative stress, 4d showing the highest activity.
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Noble metal nanoparticle-induced oxidative stress modulates tumor associated macrophages (TAMs) from an M2 to M1 phenotype: An in vitro approach.
Ramkrishna Pal,Biswajit Chakraborty,Anupam Nath,Leichombam Mohindro Singh,Mohammed A. H. Ali,Dewan S. Rahman,Sujit Kumar Ghosh,Abhishek Basu,Sudin Bhattacharya,Rathindranath Baral,Mahuya Sengupta +10 more
TL;DR: The intrinsic properties of noble metal NPs (gold and silver) as well as the mechanism of their potential antitumor activity are addressed, seen that AuNPs and AgNPs modulate the reactive oxygen species (ROS) and reactive nitrogen Species (RNS) production, suppressing the antioxidant system of cells (TAMs).
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Selenium nanoparticles are less toxic than inorganic and organic selenium to mice in vivo
TL;DR: It is suggested that Nano-Se as an antioxidant can serve as a potential chemopreventive agent with reduced risk of selenium toxicity and caused less bone marrow cell death and prevented DNA damage, compared to other forms of Selenium.