Showing papers by "Sudipta Saha published in 2008"
Journal Article•
TL;DR: A rare case of cryptococcal jejunal perforation, which was the initial presentation in an AIDS patient, and ELISA was reactive for HIV-1 antibody.
Abstract: A 30-year-old woman underwent exploratory laparotomy for perforation peritonitis. Primary repair of the jejunal perforation was performed. The ulcer edge biopsy revealed Cryptococcus. Subsequently ELISA was reactive for HIV-1 antibody. This report describes a rare case of cryptococcal jejunal perforation, which was the initial presentation in an AIDS patient.
14 citations
TL;DR: Assessing the intra-operative tumour size in 29 patients of breast cancer presenting to a tertiary care centre in Delhi and to compare it with CE, USG and PE found all three modalities showed statistically significant correlation with IO.
Abstract: Accurate measurement of breast tumour size determines staging and prognosis. Discrepancies amongst clinical examination (CE), ultrasonography (USG), mammography, pathological examination (PE) and magnetic resonance imaging have been reported. However, few studies have evaluated changes in breast tumour size from the operating table to the laboratory. Objectives and methods: A prospective study was designed to assess the intra-operative (IO) tumour size in 29 patients of breast cancer presenting to a tertiary care centre in Delhi and to compare it with CE, USG and PE. Observations and results: Twenty-nine patients (mean age: 47 years), presenting with invasive duct carcinoma (stage IIIA: 31%, stage IIB: 28%), were included in the study. Comparison with mean IO (4.2 cm) revealed that both USG and PE underestimated tumour size by a mean of 0.35 cm (8.4%) and 0.45 cm (10.7%), respectively, in most patients. CE tended to overestimate size by 0.82 cm (19.8%). All three modalities showed statistically significant correlation with IO (maximum Pearson's correlation coefficient for PE=0.937, p<0.001; R 2 =0.877, maximum for PE). Two-way analysis of variance revealed mean difference in size to be statistically significant (p=0.000) only between CE and IO. Discussion: Formalin processing causes changes in tumour dimensions in the breast, causing reduction in tumour size. It may also have a bearing on the assessment of surgical margins in breast conservation surgery. Immediate post-operative measurement of the specimen is ideal. Protocols for specimen fixation should be standardized.
9 citations
TL;DR: High mammographic density patterns are associated with an increased risk for the development of breast cancer in younger women in a low risk population, whereas no such increase in risk is seen in postmenopausal women.
Abstract: Background: Mammographic density is a function of abundance of epithelial and connective tissue in breast. It has been identified as an independent risk factor for breast cancer in studies in western populations. We conducted a case control study to evaluate the role of mammographic density as risk factor for the development of breast cancer in Indian patients. Methods: One hundred and one cases of breast cancer and 123 healthy controls were included in the study. Mammographic density of the breast tissue of all controls and the contralateral breast of breast cancer patients was measured using a six category scale by a qualified radiologist. Results: A low prevalence of dense mammographic patterns (16.3% in controls and 26.7% in cases) was seen in the study population. Premenopausal women with breast density of 50% or more had 3.8 times risk of developing breast cancer than women with breast density of < 10%. (OR = 3.86; 95% CI = 1.4-10.1) In postmenopausal women with mammographically dense breast, no such increase in risk was noted. Conclusion: High mammographic density patterns are associated with an increased risk for the development of breast cancer in younger women in a low risk population, whereas no such increase in risk is seen in postmenopausal women.
9 citations
Journal Article•
TL;DR: Investigation revealed a bladder calculus encrusted on an intrauterine device (IUD), which was probably inserted 20 years back at the time of medical termination of pregnancy, which led to a 45 year old lady presenting with cystitis.
Abstract: Bladder calculi are uncommon in adults and usually result either from obstruction or foreign bodies. The present case report describes a 45 year old lady presenting with cystitis. Investigations revealed a bladder calculus encrusted on an intrauterine device (IUD), which was probably inserted 20 years back at the time of medical termination of pregnancy. Ballistic lithotripsy of the bladder stone with cystoscopic extraction of the IUD was successfully carried out.
1 citations