Sue Kim

TL;DR: Patient-specific, immune-matched human embryonic stem cells (hESCs) are anticipated to be of great biomedical importance for studies of disease and development and to advance clinical deliberations regarding stem cell transplantation, but before clinical use of these cells can occur, preclinical evidence is required to prove that transplantation of differentiated NT-hESC can be safe, effective, and tolerated.

TL;DR: Patient-specific, immune-matched human embryonic stem cells (hESCs) are anticipated to be of great biomedical importance for studies of disease and development and to advance clinical deliberations regarding stem cell transplantation, but before clinical use of these cells can occur, preclinical evidence is required to prove that transplantation of differentiated NT-hESC can be safe, effective, and tolerated.

TL;DR: The pregnancy rates in SCNT embryos derived from sow oocytes were higher than those with gilt oocytes regardless of donor cell types, and the ratio of inner cell mass (ICM)/total cells in G-E FA and S-EFA was significantly lower than in the other groups.

TL;DR: The results revealed that 100 pM was the optimal concentration, which resulted in significantly increased cleavage and blastocyst formation rates and the total cell numbers in blastocysts were significantly higher when the embryos were cultured with melatonin.

TL;DR: A system for porcine SCNT was developed and led to the successful production of hEPO transgenic cloned piglets, and the effect of elevated Ca2+ concentration in the fusion/activation medium on development of transfected SCNT embryos was investigated.