Suheib S. Abukmeil

TL;DR: Several brain structures in schizophrenia are affected to a greater extent than expected from overall reductions in brain volume, and substantial reductions were also evident in the amygdala and hippocampus.

TL;DR: People at high risk of developing schizophrenia for genetic reasons have several structural brain abnormalities that are similar to those in patients with the disorder, and at-risk individuals with particularly small AHC or thalami are most likely to develop schizophrenia.

TL;DR: The results suggest that some structural abnormalities in subjects at high risk of developing schizophrenia have abnormalities of brain structure similar to but not identical to those found in schizophrenia, and that the development of symptoms is associated with a third overlapping group of structural changes.

TL;DR: The results suggest that the development of psychotic symptoms is preceded by a decline in IQ and memory, which may reflect a general and a more specific disease process respectively.

TL;DR: Comparisons of the high risk subjects, well controls and subjects with first-episode schizophrenia in terms of demographic, childhood, psychopathological, educational and employment, forensic and social work variables are presented.