S
Sukhneeraj P. Kaur
Researcher at University of Georgia
Publications - 5
Citations - 68
Sukhneeraj P. Kaur is an academic researcher from University of Georgia. The author has contributed to research in topics: Tumor microenvironment & Stromal cell. The author has an hindex of 4, co-authored 5 publications receiving 43 citations. Previous affiliations of Sukhneeraj P. Kaur include Panjab University, Chandigarh.
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Journal ArticleDOI
Role of glypicans in regulation of the tumor microenvironment and cancer progression.
TL;DR: Glypicans have emerged as a new therapeutic moiety, whose functions can be exploited in the field of targeted therapies and precision medicine in cancer, demonstrated by the emergence of several anti-glypican antibody-based immunologics that have been recently developed and are being evaluated in clinal trials.
Journal ArticleDOI
Paradoxical Role of Glypican-1 in Prostate Cancer Cell and Tumor Growth
Nhat D. Quach,Sukhneeraj P. Kaur,Matthew Eggert,Lishann M. Ingram,Deepraj Ghosh,Sheela Sheth,Tamas Nagy,Michelle R. Dawson,Robert D. Arnold,Robert D. Arnold,Brian S. Cummings +10 more
TL;DR: The paradoxical role that GPC-1 plays in prostate cancer cell growth by interacting with stromal cells and through ECM remodeling and endocrine/paracrine signaling is demonstrated by test of tumor conditioned media on gene expression in human mesenchymal stem cells and fibroblasts.
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17α-Estradiol: a candidate neuroserm and non-feminizing estrogen for postmenopausal neuronal complications.
TL;DR: 17α-Estradiol (E2α), a non feminizing congener, gives a ray of hope to the scientific community as an alternative strategy to treat menopause associated neuronal pathologies and offers safe alternative to E2 in protecting against menopausal neuropathologies.
Journal ArticleDOI
Bromate-induced Changes in p21 DNA Methylation and Histone Acetylation in Renal Cells.
Ramya T Kolli,Travis C. Glenn,Bradley T. Brown,Sukhneeraj P. Kaur,Lillie M. Barnett,Lawrence H. Lash,Brian S. Cummings +6 more
TL;DR: Novel sites within the p21 gene that are epigenetically regulated are demonstrated and further show that significant differences exist in the epigenetic landscape between rat and human p21, especially with regards to toxicant-induced changes in histone acetylation.
Journal ArticleDOI
Inhibition of glypican-1 expression induces an activated fibroblast phenotype in a human bone marrow-derived stromal cell-line.
Sukhneeraj P. Kaur,Arti Verma,Hee. K. Lee,Lillie M. Barnett,Payaningal R. Somanath,Payaningal R. Somanath,Brian S. Cummings +6 more
TL;DR: In this article, the significance of glypican-1 (GPC-1), a heparan sulfate proteoglycan, in regulating the activation of human bone marrow-derived stromal cells of fibroblast lineage (HS-5) was elucidated.