S
Sunil Lekhak
Researcher at Kathmandu
Publications - 9
Citations - 285
Sunil Lekhak is an academic researcher from Kathmandu. The author has contributed to research in topics: Agar diffusion test & Minimum inhibitory concentration. The author has an hindex of 4, co-authored 8 publications receiving 247 citations. Previous affiliations of Sunil Lekhak include Kathmandu Medical College & Tribhuvan University.
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Antibacterial Property of Different Medicinal Plants: Ocimum sanctum, Cinnamomum zeylanicum, Xanthoxylum armatum and Origanum majorana
Sunil Lekhak,Anuja Sharma +1 more
TL;DR: From the screening experiment, Origanum majorana showed the best antibacterial activity; hence this plant can be further subjected to isolation of the therapeutic antimicrobials and pharmacological evaluation.
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Extended spectrum β-lactamase producing uropathogenic Escherichia coli and the correlation of biofilm with antibiotics resistance in Nepal.
Raju Shrestha,Santosh Khanal,Pramod Poudel,Karan Khadayat,Sajani Ghaju,Anita Bhandari,Sunil Lekhak,Narayan Dutt Pant,Manisha Sharma,Bishnu P. Marasini +9 more
TL;DR: A weak positive correlation between biofilm and ESBL production is presented in which biofilm producing UPEC harbors both pgaA and pgaC genes responsible for biofilm formation.
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Evaluation of multiplex PCR using MPB64 and IS6110 primers for rapid diagnosis of tuberculous meningitis
Sunil Lekhak,Sunil Lekhak,Laxmi Sharma,Reema Rajbhandari,Pravesh Rajbhandari,Resha Shrestha,Basant Pant +6 more
TL;DR: Evaluating the Multiplex polymerase chain reaction (PCR) technique, using primers directed against the insertion sequence IS6110 and MPB64 gene for the detection of Mycobacterium tuberculosis in Cerebrospinal fluid (CSF), found it to have high sensitivity and could be used for the early detection of TBM in CSF samples.
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Glucose 6 phosphate dehydrogenase deficiency and hemoglobinopathy in South Western Region Nepal: a boon or burden.
Narayan Gautam,Bhagwati Gaire,Trishna Manandhar,Bishnu P. Marasini,Niranjan Parajuli,Sunil Lekhak,Monica Nepal +6 more
TL;DR: The study highlighted sickle cell disorder (SCD) and β-TT as the most common hemoglobinopathy coexisting with G6PD deficiency, which can cause massive hemolysis which may exacerbate the condition.
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Detection of blaNDM-1 gene among the carbapenem resistant Escherichia coli and Klebsiella pneumoniae isolates from a children’s hospital in Nepal
Binod G C,Nim Raj Sapkota,Binod Rayamajhee,Jayram Lamichhane,Pramod Poudel,Sunil Lekhak,Shovana Thapa,Santosh Khanal +7 more
TL;DR: Results of this study demonstrated the presence of blaNDM-1 gene among the carbapenemase producing E. coli and K. pneumoniae isolates to be 50% and 66.6%,respectively.