Surita Banwait

TL;DR: It is reported that in patients with stroke, cells that express markers associated with newborn neurons are present in the ischemic penumbra surrounding cerebral cortical infarcts, where these cells are preferentially localized in the vicinity of blood vessels.

TL;DR: It is suggested that Asp-664 plays a critical role in the generation of Alzheimer-related pathophysiological and behavioral changes in human APP transgenic mice, possibly as a cleavage site or via protein-protein interactions.

TL;DR: Evidence is provided that VEGF increases SVZ neurogenesis and neuromigration, consistent with a possible role in repair, and suggests that in addition to its neuroprotective effects, V EGF enhances postischemic neuroGenesis, which could provide a therapeutic target for more chronic brain repair.

TL;DR: Transplantation of neural precursors by a variety of routes can deliver cells with the potential to replace injured neurons to ischemic brain regions and enhance their migration when delivered by any of these routes.

TL;DR: It is reported that S OD1G93A/VEGF+/+ double-transgenic mice show delayed motor neuron loss, delayed motor impairment, and prolonged survival compared with SOD1G 93A single transgenics.