S
Susan V. Castro
Researcher at Thomas Jefferson University
Publications - 3
Citations - 331
Susan V. Castro is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Vascular endothelial growth factor A & Platelet-derived growth factor receptor. The author has an hindex of 3, co-authored 3 publications receiving 309 citations.
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Narrative Review: Fibrotic Diseases: Cellular and Molecular Mechanisms and Novel Therapies
TL;DR: The inhibition of signaling pathways activated by TGF-beta represents a novel therapeutic approach for the fibrotic disorders and results in the activation of the nonreceptor tyrosine kinase cellular Abelson, and c-Abl inhibitors, diminishing the fibrogenic effects of TGF -beta.
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Biomarkers in systemic sclerosis.
TL;DR: There is an unmet need for validated biomarkers for diagnosis, disease classification, and evaluation of organ involvement and therapeutic response in systemic sclerosis.
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Role of Growth Factors in the Pathogenesis of Tissue Fibrosis in Systemic Sclerosis
TL;DR: The experimental evidence supporting the participation of various growth factors in the pathogenesis of the fibrotic process in SSc and the molecular mechanisms involved will be reviewed.