S
Sushmita Paul
Researcher at Indian Institute of Technology, Jodhpur
Publications - 62
Citations - 712
Sushmita Paul is an academic researcher from Indian Institute of Technology, Jodhpur. The author has contributed to research in topics: Cluster analysis & Rough set. The author has an hindex of 12, co-authored 57 publications receiving 575 citations. Previous affiliations of Sushmita Paul include University of Erlangen-Nuremberg & Indian Statistical Institute.
Papers
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Rough set based maximum relevance-maximum significance criterion and Gene selection from microarray data
Pradipta Maji,Sushmita Paul +1 more
TL;DR: A new feature selection algorithm is presented based on rough set theory that selects a set of genes from microarray data by maximizing the relevance and significance of the selected genes.
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Rough-Fuzzy Clustering for Grouping Functionally Similar Genes from Microarray Data
Pradipta Maji,Sushmita Paul +1 more
TL;DR: An efficient method is proposed to select initial prototypes of different gene clusters, which enables the proposed c-means algorithm to converge to an optimum or near optimum solutions and helps to discover coexpressed gene clusters.
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The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.
Nicole Hannemann,Jutta Jordan,Sushmita Paul,Stephen Reid,H. W. Baenkler,Sophia Sonnewald,Tobias Bäuerle,Julio Vera,Georg Schett,Aline Bozec +9 more
TL;DR: In vivo and in vitro gene profiling, together with chromatin immunoprecipitation analysis of macrophages, revealed direct activation of the proinflammatory factor cyclooxygenase-2 and indirect inhibition of the anti-inflammatory factor arginase-1 by c-Jun.
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EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells
Pablo Lindner,Sushmita Paul,Markus Eckstein,Chuanpit Hampel,Julienne K. Muenzner,Katharina Erlenbach-Wuensch,Husayn P Ahmed,Vijayalakshmi Mahadevan,Thomas Brabletz,Arndt Hartmann,Julio Vera,Regine Schneider-Stock +11 more
TL;DR: This study demonstrates a novel example of an activator role of ZEB1 for the epigenetic landscape in colorectal tumor cells and identifies a self-reinforcing loop for Z EB1 expression and found that the SETD1B associated active chromatin mark H3K4me3 was enriched at the ZEB 1 promoter in EMT cells.
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Rough Sets for Selection of Molecular Descriptors to Predict Biological Activity of Molecules
Pradipta Maji,Sushmita Paul +1 more
TL;DR: A new feature selection algorithm is presented, based on rough set theory, to select a set of effective molecular descriptors from a given QSAR dataset by maximizing both relevance and significance of the descriptors.