A
Arndt Hartmann
Researcher at University of Erlangen-Nuremberg
Publications - 1023
Citations - 45826
Arndt Hartmann is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 93, co-authored 895 publications receiving 35827 citations. Previous affiliations of Arndt Hartmann include University of Basel & University of Jena.
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Journal ArticleDOI
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer
A. Gordon Robertson,Jaegil Kim,Hikmat Al-Ahmadie,Joaquim Bellmunt,Guangwu Guo,Andrew D. Cherniack,Toshinori Hinoue,Peter W. Laird,Katherine A. Hoadley,Rehan Akbani,Mauro A. A. Castro,Ewan A. Gibb,Rupa S. Kanchi,Dmitry A. Gordenin,Sachet A. Shukla,Francisco Sanchez-Vega,Donna E. Hansel,Bogdan Czerniak,Victor E. Reuter,Xiaoping Su,Benilton S. Carvalho,Vinicius S Chagas,Karen Mungall,Sara Sadeghi,Chandra Sekhar Pedamallu,Yiling Lu,Leszek J. Klimczak,Jiexin Zhang,Caleb Choo,Akinyemi I. Ojesina,Susan Bullman,Kristen M. Leraas,Tara M. Lichtenberg,Catherine J. Wu,N. Schultz,Gad Getz,Matthew Meyerson,Gordon B. Mills,David J. McConkey,Monique Albert,Iakovina Alexopoulou,Adrian Ally,Tatjana Antic,Manju Aron,Miruna Balasundaram,John M. S. Bartlett,Stephen B. Baylin,Allison Beaver,Inanc Birol,Lori Boice,Moiz S. Bootwalla,Jay Bowen,Reanne Bowlby,Denise Brooks,Bradley M. Broom,Wiam Bshara,Eric J. Burks,Flavio Mavignier Carcano,Rebecca Carlsen,André Lopes Carvalho,Eric P. Castle,Patricia Castro,James W.F. Catto,David Chesla,Eric Chuah,Sudha Chudamani,Victoria K. Cortessis,Sandra Cottingham,Daniel Crain,Erin Curley,Siamak Daneshmand,John A. Demchok,Noreen Dhalla,Hooman Djaladat,John Eckman,Sophie C. Egea,Jay Engel,Ina Felau,Martin L. Ferguson,Johanna Gardner,Julie M. Gastier-Foster,Mark Gerken,Carmen Gomez-Fernandez,Jodi Harr,Arndt Hartmann,Lynn M. Herbert,Thai H. Ho,Robert A. Holt,Carolyn M. Hutter,Steven J.M. Jones,Merce Jorda,Richard J. Kahnoski,Katayoon Kasaian,David J. Kwiatkowski,Phillip H. Lai,Brian R. Lane,Seth P. Lerner,Jia Liu,Laxmi Lolla,Yair Lotan,Fabiano R. Lucchesi,Yussanne Ma,Roberto Dias Machado,Dennis T. Maglinte,David Mallery,Marco A. Marra,Sue E. Martin,Michael Mayo,Anoop Meraney,Alireza Moinzadeh,Richard A. Moore,Edna M. Mora Pinero,Scott Morris,Carl Morrison,Andrew J. Mungall,Jerome Myers,Rashi Naresh,Peter H. O'Donnell,Dipen J. Parekh,Jeremy Parfitt,Joseph Paulauskis,Robert Penny,Todd Pihl,Sima P. Porten,Mario Quintero-Aguilo,Nilsa C. Ramirez,W. Kimryn Rathmell,Kimberly M. Rieger-Christ,Charles Saller,Andrew Salner,George E. Sandusky,Cristovam Scapulatempo-Neto,Jacqueline E. Schein,Anne Schuckman,Candace Shelton,Troy Shelton,Jeff Simko,Parminder Singh,Payal Sipahimalani,Norm D. Smith,Heidi J. Sofia,Andrea Sorcini,Melissa L. Stanton,Gary D. Steinberg,Robert Stoehr,Travis Sullivan,Qiang Sun,Angela Tam,Roy Tarnuzzer,Katherine Tarvin,Helge Taubert,Nina Thiessen,Leigh B. Thorne,Kane Tse,Kelinda Tucker,David Van Den Berg,Kim E.M. van Kessel,Sven Wach,Yunhu Wan,Zhining Wang,John N. Weinstein,Daniel J. Weisenberger,Lisa Wise,Tina Wong,Ye Wu,Liming Yang,Leigh Anne Zach,Jean C. Zenklusen,Jiashan Zhang,Erik Zmuda,Ellen C. Zwarthoff +170 more
TL;DR: An analysis of 412 muscle-invasive bladder cancers characterized by multiple TCGA analytical platforms identified 5 expression subtypes that may stratify response to different treatments and identified a poor-survival "neuronal" subtype in which the majority of tumors lacked small cell or neuroendocrine histology.
Journal ArticleDOI
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
Katherine A Hoadley,Christina Yau,Christina Yau,Toshinori Hinoue,Denise M. Wolf,Alexander J. Lazar,Esther Drill,Ronglai Shen,Alison M. Taylor,Alison M. Taylor,Andrew D. Cherniack,Andrew D. Cherniack,Vesteinn Thorsson,Rehan Akbani,Reanne Bowlby,Christopher K. Wong,Maciej Wiznerowicz,Maciej Wiznerowicz,Francisco Sanchez-Vega,A. Gordon Robertson,Barbara G. Schneider,Michael S. Lawrence,Michael S. Lawrence,Houtan Noushmehr,Houtan Noushmehr,Tathiane M. Malta,Tathiane M. Malta,Samantha J. Caesar-Johnson,John A. Demchok,Ina Felau,Melpomeni Kasapi,Martin L. Ferguson,Carolyn M. Hutter,Heidi J. Sofia,Roy Tarnuzzer,Zhining Wang,Liming Yang,Jean C. Zenklusen,Jiashan Zhang,Sudha Chudamani,Jia Liu,Laxmi Lolla,Rashi Naresh,Todd Pihl,Qiang Sun,Yunhu Wan,Ye Wu,Juok Cho,Timothy Defreitas,Scott Frazer,Nils Gehlenborg,Gad Getz,David I. Heiman,Jaegil Kim,Pei Lin,Sam Meier,Michael S. Noble,Gordon Saksena,Doug Voet,Hailei Zhang,Brady Bernard,Nyasha Chambwe,Varsha Dhankani,Theo A. Knijnenburg,Roger Kramer,Kalle Leinonen,Yuexin Liu,Michael W. Miller,Sheila Reynolds,Ilya Shmulevich,Wei Zhang,Bradley M. Broom,Apurva M. Hegde,Zhenlin Ju,Rupa S. Kanchi,Anil Korkut,Jun Li,Han Liang,Shiyun Ling,Wen-Bin Liu,Yiling Lu,Gordon B. Mills,Kwok Shing Ng,Arvind Rao,Michael T. Ryan,Jing Wang,John N. Weinstein,Jiexin Zhang,Adam Abeshouse,Joshua Armenia,Debyani Chakravarty,Walid K. Chatila,Ino de Bruijn,Jianjiong Gao,Benjamin Gross,Zachary J. Heins,Ritika Kundra,Konnor La,Marc Ladanyi,Augustin Luna,Moriah G. Nissan,Angelica Ochoa,Sarah Phillips,Ed Reznik,Chris Sander,Nikolaus Schultz,Robert L. Sheridan,S. Onur Sumer,Yichao Sun,Barry S. Taylor,Jioajiao Wang,Hongxin Zhang,Pavana Anur,Myron Peto,Paul T. Spellman,Christopher C. Benz,Joshua M. Stuart,D. Neil Hayes,Joel S. Parker,Matthew D. Wilkerson,Adrian Ally,Miruna Balasundaram,Denise Brooks,Rebecca Carlsen,Eric Chuah,Noreen Dhalla,Robert A. Holt,Steven J.M. Jones,Katayoon Kasaian,Darlene Lee,Yussanne Ma,Marco A. Marra,Michael Mayo,Richard A. Moore,Andrew J. Mungall,Karen Mungall,Sara Sadeghi,Jacqueline E. Schein,Payal Sipahimalani,Angela Tam,Nina Thiessen,Kane Tse,Tina Wong,Ashton C. Berger,Rameen Beroukhim,Carrie Cibulskis,Stacey Gabriel,Galen F. Gao,Gavin Ha,Matthew Meyerson,Steven E. Schumacher,Juliann Shih,Melanie H. Kucherlapati,Raju Kucherlapati,Stephen B. Baylin,Leslie Cope,Ludmila Danilova,Moiz S. Bootwalla,Phillip H. Lai,Dennis T. Maglinte,David Van Den Berg,Daniel J. Weisenberger,J. Todd Auman,Saianand Balu,Tom Bodenheimer,Cheng Fan,Alan P. Hoyle,Stuart R. Jefferys,Corbin D. Jones,Shaowu Meng,Piotr A. Mieczkowski,Lisle E. Mose,Amy H. Perou,Charles M. Perou,Jeffrey Roach,Yan Shi,Janae V. Simons,Tara Skelly,Matthew G. Soloway,Donghui Tan,Umadevi Veluvolu,Huihui Fan,Peter W. Laird,Hui Shen,Wanding Zhou,Michelle Bellair,Kyle Chang,Kyle R. Covington,Chad J. Creighton,Huyen Dinh,Harshavardhan Doddapaneni,Lawrence A. Donehower,Jennifer Drummond,Richard A. Gibbs,Robert Glenn,Walker Hale,Yi Han,Jianhong Hu,Viktoriya Korchina,Sandra J. Lee,Lora Lewis,W. G. Li,Xiuping Liu,Margaret Morgan,Donna Morton,Donna M. Muzny,Jireh Santibanez,Margi Sheth,Eve Shinbrot,Linghua Wang,Min Wang,David A. Wheeler,Liu Xi,Fengmei Zhao,Julian M. Hess,Elizabeth L. Appelbaum,Matthew A. Bailey,Matthew G. Cordes,Li Ding,Catrina Fronick,Lucinda Fulton,Robert S. Fulton,Cyriac Kandoth,Elaine R. Mardis,Michael D. McLellan,Christopher A. Miller,Heather Schmidt,Rick K. Wilson,Daniel Crain,Erin Curley,Johanna Gardner,Kevin Lau,David Mallery,Scott Morris,Joseph Paulauskis,Robert Penny,Candace Shelton,Troy Shelton,Mark E. Sherman,Eric M. Thompson,Peggy Yena,Jay Bowen,Julie M. Gastier-Foster,Mark Gerken,Kristen M. Leraas,Tara M. Lichtenberg,Nilsa C. Ramirez,Lisa Wise,Erik Zmuda,Niall M. Corcoran,Tony Costello,Christopher M. Hovens,André Lopes Carvalho,Ana Carolina de Carvalho,José Humberto Tavares Guerreiro Fregnani,Adhemar Longatto-Filho,Rui Manuel Reis,Cristovam Scapulatempo-Neto,Henrique César Santejo Silveira,Daniel Onofre Vidal,Andrew Burnette,Jennifer M. Eschbacher,Beth Hermes,Ardene Noss,Rosy Singh,Matthew L. Anderson,Patricia Castro,Michael Ittmann,David G. Huntsman,Bernard Kohl,Xuan Le,Richard Thorp,Chris Andry,Elizabeth R. Duffy,Vladimir Lyadov,Oxana Paklina,Galiya Setdikova,Alexey Shabunin,Mikhail Tavobilov,Christopher M. McPherson,Ronald E. Warnick,Ross S. Berkowitz,Daniel W. Cramer,Colleen M. Feltmate,Neil S. Horowitz,Adam S. Kibel,Michael G. Muto,Chandrajit P. Raut,Andrei Malykh,Jill S. Barnholtz-Sloan,Wendi Barrett,Karen Devine,Jordonna Fulop,Quinn T. Ostrom,Kristen Shimmel,Yingli Wolinsky,Andrew E. Sloan,Agostino Maria De Rose,Felice Giuliante,Marc T. Goodman,Beth Y. Karlan,Curt H. Hagedorn,John Eckman,Jodi Harr,Jerome Myers,Kelinda Tucker,Leigh Anne Zach,Brenda Deyarmin,Hai Hu,Leonid Kvecher,Caroline Larson,Richard J. Mural,Stella Somiari,Ales Vicha,Tomáš Zelinka,Joseph J. Bennett,Mary Iacocca,Brenda Rabeno,Patricia Swanson,Mathieu Latour,Louis Lacombe,Bernard Têtu,Alain Bergeron,Mary McGraw,Susan M. Staugaitis,John Chabot,Hanina Hibshoosh,Antonia R. Sepulveda,Tao Su,Timothy C. Wang,Olga Potapova,Olga Voronina,Laurence Desjardins,Odette Mariani,Sergio Roman-Roman,Xavier Sastre,Marc-Henri Stern,Feixiong Cheng,Sabina Signoretti,Andrew Berchuck,Darell D. Bigner,Eric S. Lipp,Jeffrey R. Marks,Shannon J. McCall,Roger E. McLendon,Angeles Alvarez Secord,Alexis Sharp,Madhusmita Behera,Daniel J. Brat,Amy Y. Chen,Keith A. Delman,Seth D. Force,Fadlo R. Khuri,Kelly R. Magliocca,Shishir K. Maithel,Jeffrey J. Olson,Taofeek K. Owonikoko,Alan Pickens,Suresh S. Ramalingam,Dong M. Shin,Gabriel Sica,Erwin G. Van Meir,Hongzheng Zhang,Wil Eijckenboom,Ad J. M. Gillis,Esther Korpershoek,Leendert H. J. Looijenga,Wolter Oosterhuis,Hans Stoop,Kim E.M. van Kessel,Ellen C. Zwarthoff,Chiara Calatozzolo,Lucia Cuppini,Stefania Cuzzubbo,Francesco DiMeco,Gaetano Finocchiaro,Luca Mattei,Alessandro Perin,Bianca Pollo,Chu Chen,John Houck,Pawadee Lohavanichbutr,Arndt Hartmann,Christine Stoehr,Robert Stoehr,Helge Taubert,Sven Wach,Bernd Wullich,Witold Kycler,Dawid Murawa,Ki Chung,W. Jeffrey Edenfield,Julie S. Martin,Eric Baudin,Glenn J. Bubley,Raphael Bueno,Assunta De Rienzo,William G. Richards,Steven N. Kalkanis,Tom Mikkelsen,Lisa Scarpace,Nicolas Girard,Marta Aymerich,Elias Campo,Eva Giné,Armando López Guillermo,Nguyen Van Bang,Phan Thi Hanh,Bui Duc Phu,Yufang Tang,Howard Colman,Kimberley Evason,Peter Dottino,John A. Martignetti,Hani Gabra,Hartmut Juhl,Teniola Akeredolu,Serghei Stepa,Dave S.B. Hoon,Keunsoo Ahn,Koo Jeong Kang,Felix Beuschlein,Anne Breggia,Michael J. Birrer,Debra A. Bell,Mitesh J. Borad,Alan H. Bryce,Erik P. Castle,Vishal S. Chandan,John C. Cheville,John A. Copland,Michael B. Farnell,Thomas J. Flotte,Nasra H. Giama,Thai H. Ho,Michael L. Kendrick,Jean Pierre A. Kocher,Karla Kopp,Catherine D. Moser,David M. Nagorney,Daniel R. O'Brien,Brian P. O'Neill,Tushar Patel,Gloria M. Petersen,Florencia G. Que,Michael Rivera,Lewis R. Roberts,Robert C. Smallridge,Thomas C. Smyrk,Melissa L. Stanton,R. Houston Thompson,Michael Torbenson,Ju Dong Yang,Lizhi Zhang,Fadi Brimo,Jaffer A. Ajani,Ana Maria Angulo Gonzalez,Carmen Behrens,olanta Bondaruk,Russell Broaddus,Bogdan Czerniak,Bita Esmaeli,Junya Fujimoto,Jeffrey E. Gershenwald,Charles C. Guo,Christopher J. Logothetis,Funda Meric-Bernstam,Cesar A. Moran,Lois M. Ramondetta,David C. Rice,Anil K. Sood,Pheroze Tamboli,Timothy C. Thompson,Patricia Troncoso,Anne Tsao,Ignacio I. Wistuba,Candace Carter,Lauren E. Haydu,Peter Hersey,Valerie Jakrot,Hojabr Kakavand,Richard F. Kefford,Kenneth K. Lee,Georgina V. Long,Graham J. Mann,Michael A. Quinn,Robyn P. M. Saw,Richard A. Scolyer,Kerwin F. Shannon,Andrew J. Spillane,Jonathan R. Stretch,Maria Synott,John F. Thompson,James S. Wilmott,Hikmat Al-Ahmadie,Timothy A. Chan,Ronald Ghossein,Anuradha Gopalan,Douglas A. Levine,Victor E. Reuter,Samuel Singer,Bhuvanesh Singh,Nguyen Viet Tien,Thomas Broudy,Cyrus Mirsaidi,Praveen Nair,Paul Drwiega,Judy Miller,Jennifer S. Smith,Howard Zaren,Joong-Won Park,Nguyen Phi Hung,Electron Kebebew,W. Marston Linehan,Adam R. Metwalli,Karel Pacak,Peter A. Pinto,Mark Schiffman,Laura S. Schmidt,Cathy D. Vocke,Nicolas Wentzensen,Robert Worrell,Hannah P. Yang,Marc Moncrieff,Chandra Goparaju,Jonathan Melamed,Harvey I. Pass,Natalia Botnariuc,Irina Caraman,Mircea Cernat,Inga Chemencedji,Adrian Clipca,Serghei Doruc,Ghenadie Gorincioi,Sergiu Mura,Maria Pirtac,Irina Stancul,Diana Tcaciuc,Monique Albert,Iakovina Alexopoulou,Angel Arnaout,John Bartlett,Jay Engel,Sebastien Gilbert,Jeremy Parfitt,Harman Sekhon,George Thomas,Doris M. Rassl,Robert C. Rintoul,Carlo Bifulco,Raina Tamakawa,Walter J. Urba,Nicholas K. Hayward,Henri J L M Timmers,Anna Antenucci,Francesco Facciolo,Gian Luca Grazi,Mirella Marino,Roberta Merola,Ronald R. de Krijger,Anne Paule Gimenez-Roqueplo,Alain Piché,Simone Chevalier,Ginette McKercher,Kıvanç Birsoy,Gene H. Barnett,Cathy Brewer,Carol Farver,Theresa Naska,Nathan A. Pennell,Daniel P. Raymond,Cathy Schilero,Kathy Smolenski,Felicia Williams,Carl Morrison,Jeffrey A. Borgia,Michael J. Liptay,Mark Pool,Christopher W. Seder,Kerstin Junker,Larsson Omberg,Mikhail Dinkin,George Manikhas,Domenico Alvaro,Maria Consiglia Bragazzi,Vincenzo Cardinale,Guido Carpino,Eugenio Gaudio,David Chesla,Sandra Cottingham,Michael Dubina,Fedor Moiseenko,Renumathy Dhanasekaran,Karl-Friedrich Becker,Klaus-Peter Janssen,Julia Slotta-Huspenina,Mohamed H. Abdel-Rahman,Dina Aziz,Sue E. Bell,Colleen M. Cebulla,Amy Davis,Rebecca Duell,J. Bradley Elder,Joe Hilty,Bahavna Kumar,James C. Lang,Norman L. Lehman,Randy Mandt,Phuong Nguyen,Robert Pilarski,Karan Rai,Lynn Schoenfield,Kelly Senecal,Paul Wakely,Paul Hansen,Ronald Lechan,James Powers,Arthur S. Tischler,William E. Grizzle,Katherine C. Sexton,Alison Kastl,Joel M. Henderson,Sima P. Porten,Jens Waldmann,Martin Fassnacht,Sylvia L. Asa,Dirk Schadendorf,Marta Couce,Markus Graefen,Hartwig Huland,Guido Sauter,Thorsten Schlomm,Ronald Simon,Pierre Tennstedt,Oluwole Olabode,Mark Nelson,Oliver F. Bathe,Peter R. Carroll,June M. Chan,Philip J. DiSaia,Pat Glenn,Robin Kate Kelley,Charles N. Landen,Joanna J. Phillips,Michael D. Prados,Jeffry P. Simko,Karen Smith-McCune,Scott R. VandenBerg,Kevin K. Roggin,Ashley Fehrenbach,Ady Kendler,Suzanne Sifri,Ruth Steele,Antonio Jimeno,Francis Carey,Ian Forgie,Massimo Mannelli,Michael E. Carney,Brenda Y. Hernandez,Benito Campos,Christel Herold-Mende,Christin Jungk,Andreas Unterberg,Andreas von Deimling,Aaron D. Bossler,Joseph Galbraith,Laura Jacobus,Michael Knudson,Tina Knutson,Deqin Ma,Mohammed M. Milhem,Rita Sigmund,Andrew K. Godwin,Rashna Madan,Howard G. Rosenthal,Clement Adebamowo,Sally N. Adebamowo,Alex Boussioutas,David G. Beer,Thomas J. Giordano,Anne Marie Mes-Masson,Fred Saad,Thèrése Bocklage,Lisa M. Landrum,Robert S. Mannel,Kathleen N. Moore,Katherine M. Moxley,Russel Postier,Joan L. Walker,Rosemary E. Zuna,Michael Feldman,Federico Valdivieso,Rajiv Dhir,James D. Luketich,Edna M. Mora Pinero,Mario Quintero-Aguilo,Carlos Gilberto Carlotti,Jose Sebastião Dos Santos,Rafael Kemp,Ajith Sankarankuty,Daniela Pretti da Cunha Tirapelli,James W.F. Catto,Kathy Agnew,Elizabeth M. Swisher,Jenette Creaney,Bruce W. S. Robinson,Carl Simon Shelley,Eryn M. Godwin,Sara Kendall,Cassaundra Shipman,Carol R. Bradford,Thomas E. Carey,Andrea Haddad,Jeffey Moyer,Lisa A. Peterson,Mark E. Prince,Laura S. Rozek,Gregory T. Wolf,Rayleen V. Bowman,Kwun M. Fong,Ian A. Yang,Robert Korst,W. Kimryn Rathmell,J. Leigh Fantacone-Campbell,Jeffrey A. Hooke,Albert J. Kovatich,Craig D. Shriver,John F. DiPersio,Bettina F. Drake,Ramaswamy Govindan,Sharon Heath,Timothy J. Ley,Brian A. Van Tine,Peter Westervelt,Mark A. Rubin,Jung Il Lee,Natália D. Aredes,Armaz Mariamidze,Christopher C. Benz +738 more
TL;DR: Molecular similarities among histologically or anatomically related cancer types provide a basis for focused pan-cancer analyses, such as pan-gastrointestinal, Pan-gynecological, pan-kidney, and pan-squamous cancers, and those related by stemness features, which may inform strategies for future therapeutic development.
Journal ArticleDOI
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Franck Pagès,Bernhard Mlecnik,Florence Marliot,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Fang Shu Ou,Carlo Bifulco,Alessandro Lugli,Inti Zlobec,Tilman T. Rau,Martin D. Berger,Iris D. Nagtegaal,Elisa Vink-Börger,Arndt Hartmann,Carol Geppert,Julie Kolwelter,Susanne Merkel,Robert Grützmann,Marc Van den Eynde,Anne Jouret-Mourin,Alex Kartheuser,Daniel Léonard,Christophe Remue,Julia Y. Wang,Julia Y. Wang,Prashant Bavi,Michael H.A. Roehrl,Michael H.A. Roehrl,Michael H.A. Roehrl,Pamela S. Ohashi,Linh T. Nguyen,Seong Jun Han,Heather L. MacGregor,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Giuseppe Masucci,Emilia Andersson,Eva Zavadova,Michal Vocka,Jan Spacek,Lubos Petruzelka,Bohuslav Konopasek,Pavel Dundr,Helena Skalova,Kristyna Nemejcova,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Gennaro Ciliberto,Michele Maio,Luigi Laghi,Fabio Grizzi,Tessa Fredriksen,Tessa Fredriksen,Tessa Fredriksen,Bénédicte Buttard,Bénédicte Buttard,Bénédicte Buttard,Mihaela Angelova,Mihaela Angelova,Mihaela Angelova,Angela Vasaturo,Angela Vasaturo,Angela Vasaturo,Pauline Maby,Pauline Maby,Pauline Maby,Sarah E. Church,Helen K. Angell,Lucie Lafontaine,Lucie Lafontaine,Lucie Lafontaine,Daniela Bruni,Daniela Bruni,Daniela Bruni,Carine El Sissy,Nacilla Haicheur,Amos Kirilovsky,Anne Berger,Christine Lagorce,Jeffrey P. Meyers,Christopher Paustian,Zipei Feng,Carmen Ballesteros-Merino,Jeroen R. Dijkstra,Carlijn van de Water,Shannon van Vliet,Nikki Knijn,Ana Maria Mușină,Dragos Viorel Scripcariu,Boryana Popivanova,Mingli Xu,Tomonobu Fujita,Shoichi Hazama,Nobuaki Suzuki,Hiroaki Nagano,Kiyotaka Okuno,Toshihiko Torigoe,Noriyuki Sato,Tomohisa Furuhata,Ichiro Takemasa,Kyogo Itoh,P. Patel,Hemangini H. Vora,Birva Shah,Jayendrakumar B. Patel,Kruti N. Rajvik,Shashank J. Pandya,Shilin N. Shukla,Yili Wang,Guanjun Zhang,Yutaka Kawakami,Francesco M. Marincola,Paolo A. Ascierto,Daniel J. Sargent,Bernard A. Fox,Bernard A. Fox,Jérôme Galon,Jérôme Galon,Jérôme Galon +120 more
TL;DR: The immunoscore provides a reliable estimate of the risk of recurrence in patients with colon cancer and supports the implementation of the consensus Immunoscore as a new component of a TNM-Immune classification of cancer.
Journal ArticleDOI
Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
Carsten Denkert,Gunter von Minckwitz,Silvia Darb-Esfahani,Bianca Lederer,Barbara Ingold Heppner,Karsten Weber,Jan Budczies,Jens Huober,Frederick Klauschen,Jenny Furlanetto,Wolfgang D. Schmitt,Jens-Uwe Blohmer,Thomas Karn,Berit M. Pfitzner,Sherko Kümmel,Knut Engels,Andreas Schneeweiss,Arndt Hartmann,Aurelia Noske,Peter A. Fasching,Christian Jackisch,Marion van Mackelenbergh,Peter Sinn,Christian Schem,Claus Hanusch,Michael Untch,Sibylle Loibl +26 more
TL;DR: The hypothesis that breast cancer is immunogenic and might be targetable by immune-modulating therapies is supported and increased TIL concentration predicted response to neoadjuvant chemotherapy in all molecular subtypes assessed.
Journal ArticleDOI
Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
Jérôme Galon,Jérôme Galon,Jérôme Galon,Bernhard Mlecnik,Bernhard Mlecnik,Bernhard Mlecnik,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Helen K. Angell,Helen K. Angell,Helen K. Angell,Anne Berger,Christine Lagorce,Alessandro Lugli,Inti Zlobec,Arndt Hartmann,Carlo Bifulco,Iris D. Nagtegaal,Richard Palmqvist,Giuseppe Masucci,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Michele Maio,Luigi Laghi,Fabio Grizzi,Martin Asslaber,Corrado D'Arrigo,Fernando Vidal-Vanaclocha,Eva Zavadova,Lotfi Chouchane,Pamela S. Ohashi,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Michael H.A. Roehrl,Linh V. Nguyen,Yutaka Kawakami,Shoichi Hazama,Kiyotaka Okuno,Shuji Ogino,Peter Gibbs,Paul Waring,Noriyuki Sato,Toshihiko Torigoe,Kyogo Itoh,P. Patel,Shilin N. Shukla,Yili Wang,Scott Kopetz,Frank A. Sinicrope,Viorel Scripcariu,Paolo A. Ascierto,Francesco M. Marincola,Bernard A. Fox,Bernard A. Fox,Franck Pagès +56 more
TL;DR: In colorectal cancer, the Immunoscore may add to the significance of the current AJCC/UICC TNM classification, since it has been demonstrated to be a prognostic factor superior to the AJCC or UICCTNM classification.