S
Swaminathan Srividya
Researcher at National Institute of Technology, Tiruchirappalli
Publications - 4
Citations - 99
Swaminathan Srividya is an academic researcher from National Institute of Technology, Tiruchirappalli. The author has contributed to research in topics: Docking (molecular) & Chemistry. The author has an hindex of 2, co-authored 4 publications receiving 25 citations.
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Journal ArticleDOI
Synthesis of Palladium(II) Complexes via Michael Addition: Antiproliferative Effects through ROS-Mediated Mitochondrial Apoptosis and Docking with SARS-CoV-2.
Jebiti Haribabu,Swaminathan Srividya,Dharmasivam Mahendiran,Dasararaju Gayathri,Vemula Venkatramu,Nattamai Bhuvanesh,Ramasamy Karvembu +6 more
TL;DR: For the first time, the formation of three new Pd(II) complexes through the Michael addition pathway is reported, and to the authors' surprise, binding potential of the complexes with SARS-CoV-2 main protease was higher than that with chloroquine and hydroxychloroquine.
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Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi-target inhibitors of SARS-CoV-2 and cytotoxicity
Jebiti Haribabu,Jebiti Haribabu,Vasavi Garisetti,Rahime Eshaghi Malekshah,Rahime Eshaghi Malekshah,Swaminathan Srividya,Dasararaju Gayathri,Nattamai Bhuvanesh,Ramalinga Viswanathan Mangalaraja,Cesar Echeverria,Ramasamy Karvembu +10 more
TL;DR: In this article, two heterocyclic azole compounds, 3-(2,3-dihydrobenzo[d]thiazol-2-yl)-4H-chromen-4-one (SVS1) and 5-(1H-indol-3-yl)methylene)-N-methylhydrazine-1-carbothioamide(SVS2), were obtained from 2-aminothiophenol and 4-oxo-4h-chromene-3 -carbaldehyde (for SVS1),
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Enhanced anticancer activity of half-sandwich Ru(II)-p-cymene complex bearing heterocyclic hydrazone ligand
Jebiti Haribabu,Jebiti Haribabu,Swaminathan Srividya,Reddicherla Umapathi,Dasararaju Gayathri,Pannuru Venkatesu,Nattamai Bhuvanesh,Ramasamy Karvembu +7 more
TL;DR: In this article, a hydrazone ligand was synthesized from furan-2-carbohydrazide and indole-3-carboxaldehyde, which was shown to have superior activity against A549 and HeLa cancer cells with IC50 values of 23.4 and 12.9 µm, respectively.
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Crystal structure of N-[(4-ethoxyphenyl)carbamothioyl]cyclohexanecarboxamide
TL;DR: The asymmetric unit of the title compound, C16H22N2O2S, contains two crystallographically independent molecules (A and B), which are linked via pairs of weak N—H⋯S interactions, forming inversion dimers with an R 2 2(8) ring motif for both molecules.