Background Quercetin, a well-known naturally occurring polyphenol, has recently been shown by molecular docking, in vitro and in vivo studies to be a possible anti-COVID-19 candidate. Quercetin has strong antioxidant, anti-inflammatory, immunomodulatory, and antiviral properties, and it is characterized by a very high safety profile, exerted in animals and in humans. Like most other polyphenols, quercetin shows a very low rate of oral absorption and its clinical use is considered by most of modest utility. Quercetin in a delivery-food grade system with sunflower phospholipids (Quercetin Phytosome®, QP) increases its oral absorption up to 20-fold. Methods In the present prospective, randomized, controlled, and open-label study, a daily dose of 1000 mg of QP was investigated for 30 days in 152 COVID-19 outpatients to disclose its adjuvant effect in treating the early symptoms and in preventing the severe outcomes of the disease. Results The results revealed a reduction in frequency and length of hospitalization, in need of non-invasive oxygen therapy, in progression to intensive care units and in number of deaths. The results also confirmed the very high safety profile of quercetin and suggested possible anti-fatigue and pro-appetite properties. Conclusion QP is a safe agent and in combination with standard care, when used in early stage of viral infection, could aid in improving the early symptoms and help in preventing the severity of COVID-19 disease. It is suggested that a double-blind, placebo-controlled study should be urgently carried out to confirm the results of our study.

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Possible Therapeutic Effects of Adjuvant Quercetin Supplementation Against Early-Stage COVID-19 Infection: A Prospective, Randomized, Controlled, and Open-Label Study

Moderated Mediation Analysis

COVID-19 has created a general state of worry and distress, especially among vulnerable groups such as those with psychiatric diagnoses. Worldwide, psychiatric care provision has drastically suffered during the pandemic, with many patients unable to access proper care, which may have implications for increased mental health consequences in patients with psychiatric disorders (e.g., relapse and suicide). This cross-sectional study used structural equation modeling to investigate COVID-19-related trauma and distress among Arab psychiatric population during COVID-19 quarantine. Patients with pre-existing psychiatric disorders (N = 168) completed an online survey that comprised the Depression Anxiety Stress Scale 21 (DASS-21), the Impact of Event Scale-Revised (IES-R), and a questionnaire on COVID-19-related attitudes/perceptions, sources of information, used protective measures, and socio-demographic information. Respondents commonly reported feeling down-hearted/blue, trouble concentrating, along with symptoms of avoidance and rumination related to the pandemic. Patients with depression and sleep disorders expressed higher COVID-19-related trauma than patients with other disorders. Perceived physical health mediated the effect of co-morbid chronic physical disorders on COVID-19 trauma, psychological distress, perceived vulnerability to COVID-19, and perceived likelihood of recovery in case of contracting COVID-19. Perceived physical health and perceived vulnerability to COVID-19 were strong direct predictors of COVID-19-related trauma and psychological distress. Staying at home negatively predicted COVID-19 trauma and exerted an indirect negative effect on psychological distress via COVID-19 trauma. COVID-19 trauma, age, and marital status directly predicted psychological distress, with COVID-19 trauma being the strongest predictor. Educational level, income, having family members working in the medical field, keeping up to date with the news on deaths/infected cases or the development of COVID-19 drugs or vaccines, satisfaction with available information on COVID-19, and using different protective measures were not associated with significant differences in COVID-19 trauma and psychological distress scores. Immuno-psychiatric interventions should be designed to target COVID-19-trauma and distress among younger single patients with perceived poor physical health, especially those diagnosed with depression and sleep disorders.

COVID-19-Related Psychological Trauma and Psychological Distress Among Community-Dwelling Psychiatric Patients: People Struck by Depression and Sleep Disorders Endure the Greatest Burden

Leadership Agility: Five Levels of Mastery

(2010). Strengths Based Leadership: Great Leaders, Teams, and Why People Follow. Quality Management Journal: Vol. 17, No. 1, pp. 61-62.

Strengths Based Leadership: Great Leaders, Teams, and Why People Follow

Aim This research study focused on exploring the impact of resilience on COVID-19 phobia (C19P) among individuals from different nations including a cluster of European countries, India, Indonesia, Pakistan and the United States of America (USA) Method We recruited research participants via disseminating an electronic survey on Facebook Messenger (FM) that included 812 participants The electronic survey assessed unidentifiable demographic information, the COVID-19 Phobia Scale (C19P-S;Arpaci et al , 2020) and the Brief Resilience Scale (BRS;Smith et al, 2008) Results Based on simple linear regression, resilience had a statistically significant negative affect on all four C19P factors including psychological, psychosomatic, economic and social factors (p <  001) Resilience showed a statistically significant difference for at least two nations (p <  001) investigated in this research, as shown by using the Kruskal?Wallis test Utilising linear regression analysis showed that age affects the resilience score positively significantly (p <  001) Based on the Kruskal?Wallis test, we found no statistically significant differences in resilience scores between genders, but found statistically significant differences in resilience scores based on marital status, educational level and professional status (p =  001) Conclusion We concluded that the higher the resilience level, the lower the level of C19P The level of resilience was highest in the USA, followed by Europe, Pakistan, India and Indonesia Age affected the resilience level positively and resilience differed based on marital status, education levels, and professional status but not between genders Implications are offered for effective counselling interventions during this COVID-19 pandemic and the aftermath

COVID-19 phobia across the world: Impact of resilience on COVID-19 phobia in different nations

The aim of this article is to encourage professional counselors to consider using their counseling competencies outside of the counseling field as servant leaders in organizational settings. The au...

Counselors as organizational leaders: Exploring parallels of servant leadership and professional counseling

Self-esteem reflects an individual's perception and evaluation of himself or herself, whereas, life satisfaction involves the individual's evaluation of one's life as a whole including different areas of life such as school, family and friends as well as oneself (Civitci & Civitci, 2009). The aim of the study was to investigate the relationship between self esteem and satisfaction with life in current college students. A total of 200 college students (100 Male & 100 Female) from Veer Bahadur Singh University Jaunpur (U.P.) participated. Rosenberg self-esteem scale (1965) and satisfactions with life scale (Diener et al., 1985) were administered. Self-esteem and satisfaction with life was found significantly correlated in male, female, urban and general category participants. The effect of self-esteem on satisfaction with life was found significant

Sylvia Lindinger-Sternart

Papers

COVID-19 phobia across the world: Impact of resilience on COVID-19 phobia in different nations

Counselors as organizational leaders: Exploring parallels of servant leadership and professional counseling

Self-Esteem and Life Satisfaction among University Students of Eastern Uttar Pradesh of India: A Demographical Perspective