Sylvie Ricard-Blum

TL;DR: Omics approaches including transcriptomics, proteomics, glycomics, metabolomics and interactomics, databases and computational tools for omic and multi-omic investigations of fibrosis to understand the molecular mechanisms underlying fibrogenesis and fibrosis and to identify biomarkers of diagnosis, prognosis or disease progression.

TL;DR: This chapter reports the roadmap designed to build and analyze GAG–protein interaction networks, involved in numerous biological processes such as development, angiogenesis, tumor growth, host–pathogen interactions and inflammation, extracellular matrix assembly, cell–matrix interactions and signaling.

TL;DR: In this paper, the authors investigated the potential interactions between the defence collagens C1q and MBL and the BTPs BMP-1 and mammalian tolloid-like-1 (mTLL-1).

TL;DR: This experience illustrates the ability of caplacizumab and rituximab, without hospitalization, to achieve a remission in patients with TTP and exemplifies how shared decision-making can facilitate changes of medical practice, including utilization of new treatments.

TL;DR: The interaction database MatrixDB reports protein‐protein and protein‐glycosaminoglycan interactions in human, mammalian, and model organisms, involving at least one extracellular matrix (ECM) constituent, namely full‐length proteins, ECM multimeric proteins considered as stable complexes, proteoglycans, glycosaminglycans (GAGs), and bioactive fragments called matricryptins.