S
Sylvie Ricard-Blum
Researcher at Lyon College
Publications - 113
Citations - 8656
Sylvie Ricard-Blum is an academic researcher from Lyon College. The author has contributed to research in topics: Extracellular matrix & Integrin. The author has an hindex of 38, co-authored 102 publications receiving 6749 citations. Previous affiliations of Sylvie Ricard-Blum include European Bioinformatics Institute & Centre national de la recherche scientifique.
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Journal ArticleDOI
Type III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactions.
Max H. Nanao,Sylvie Ricard-Blum,Anne Marie Di Guilmi,David Lemaire,David Lascoux,Jacqueline Chabert,Ina Attree,Andréa Dessen +7 more
TL;DR: It is demonstrated by native mass spectrometry that PcrV and PcrG expressed and purified from E. coli form a 1:1 complex in vitro, and it is shown that PCrG is highly unstable, however, it associates readily with PCrV through a region located within its first 74 amino acids to form a high affinity complex.
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Towards a unified open access dataset of molecular interactions
Pablo Porras,Elisabet Barrera,Alan Bridge,Noemi del-Toro,Gianni Cesareni,Margaret Duesbury,Margaret Duesbury,Henning Hermjakob,Marta Iannuccelli,Igor Jurisica,Igor Jurisica,Igor Jurisica,Max Kotlyar,Luana Licata,Ruth C. Lovering,David J. Lynn,Birgit H M Meldal,Bindu Nanduri,Kalpana Paneerselvam,Simona Panni,Chiara Pastrello,Matteo Pellegrini,Livia Perfetto,Negin Rahimzadeh,Prashansa Ratan,Sylvie Ricard-Blum,Lukasz Salwinski,Gautam Shirodkar,Anjalia Shrivastava,Sandra Orchard +29 more
TL;DR: This update to the work of the IMEx Consortium discusses how this initiative has been working in practice, how it has ensured database sustainability, and how it is meeting emerging annotation challenges through the introduction of new interactor types and data formats.
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Extended interaction network of procollagen C-proteinase enhancer-1 in the extracellular matrix.
Romain Salza,Franck Peysselon,Emilie Chautard,Clément Faye,Laura Moschcovich,Tali Weiss,Laure Perrin-Cocon,Laure Perrin-Cocon,Vincent Lotteau,Vincent Lotteau,Efrat Kessler,Sylvie Ricard-Blum +11 more
TL;DR: The analysis of the PC PE-1 interaction network based on Gene Ontology terms suggests that, besides its role in collagen deposition, PCPE-1 might be involved in tumour growth, neurodegenerative diseases and angiogenesis.
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Target-Derived Matricryptins Organize Cerebellar Synapse Formation through α3β1 Integrins
Jianmin Su,Renee S. Stenbjorn,Karen M. Gorse,Kaiwen Su,Kurt F. Hauser,Sylvie Ricard-Blum,Taina Pihlajaniemi,Michael A. Fox +7 more
TL;DR: It is reported that collagen XVIII and its matricryptin endostatin are generated by cerebellar Purkinje cells and are necessary for the organization of climbing fiber terminals in these neurons andendostatin is sufficient to induce climbing fiber terminal formation in vitro by binding and signaling through α3β1 integrins.
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Pro-angiogenic capacities of microvesicles produced by skin wound myofibroblasts.
Mays Merjaneh,Amélie Langlois,Sébastien Larochelle,Chanel Beaudoin Cloutier,Sylvie Ricard-Blum,Véronique J. Moulin +5 more
TL;DR: The release of microvesicles by the wound myofibroblasts brings new perspectives to the field of communication between cells during the normal healing process as well as characterize the angiogenic activity of the MVs.