T
T. Chandra
Researcher at Baylor College of Medicine
Publications - 21
Citations - 1885
T. Chandra is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Complementary DNA & Gene. The author has an hindex of 16, co-authored 21 publications receiving 1869 citations.
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Journal ArticleDOI
Complete sequence of the cDNA for human .alpha.1-antitrypsin and the gene for the S variant
TL;DR: The position and size of introns, the overall base composition, and the codon preference for the alpha 1-anti-trypsin gene differ from those for the chicken ovalbumin gene even though the two proteins belong to a common protein family, as judged by amino acid sequence homology.
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Cloned human phenylalanine hydroxylase gene allows prenatal diagnosis and carrier detection of classical phenylketonuria
TL;DR: Fe feasibility studies of prenatal diagnosis of classical phenylketonuria and identification of carriers of the trait indicate that these services could be provided for up to 75% of all families with phenyl ketonuric children in the general Caucasian population.
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Sequence homology between human alpha 1-antichymotrypsin, alpha 1-antitrypsin, and antithrombin III.
TL;DR: Comparison of the amino acid sequence of alpha 1-antichymotrypsin with that of the human alpha1-antitrypsIn has revealed a homology level similar to that between chymotRYpsin and trypsin.
Journal ArticleDOI
Cloning and sequence of cDNA coding for alpha 1-antitrypsin.
Kotoku Kurachi,T. Chandra,Sandra J. Friezner Degen,Thomas Taylor White,Thomas L. Marchioro,Savio L. C. Woo,Earl W. Davie +6 more
TL;DR: Comparison of the amino acid sequences of baboon alpha 1-antitrypsin, human antithrombin III, and chicken ovalbumin indicated that these three proteins are about 230% homologous.
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Isolation and sequence characterization of a cDNA clone of human antithrombin III
TL;DR: A human liver cDNA library was constructed by using poly(A)-containing RNA isolated from a human liver biopsy specimen by using the previously cloned baboon antithrombin III cDNA as a specific hybridization probe.