Kathryn J. H. Robson

TL;DR: DNA priming followed by MVA boosting may provide a general immunization regime for induction of high levels of CD8+ T cells and was abrogated when the order of immunization was reversed.

TL;DR: It is demonstrated that by gene targeting in a rodent Plasmodium, TRAP is critical for sporozoite infection of the mosquito salivary glands and the rat liver, and is essential for sporzoite gliding motility in vitro, suggesting that in PlasModium sporozoites, and likely in other Apicomplexa, gliding locomotion and cell invasion have a common molecular basis.

TL;DR: The cloning and sequencing of a gene from Plasmodium falciparum is reported, coding for a protein called thrombospondin related anonymous protein (TRAP), which shares certain sequence motifs common to other well-characterized proteins.

TL;DR: It is found that jointly calling variants across samples, filtering against both local and external databases, deploying multiple annotation tools and using familial transmission above biological plausibility contributed to accuracy.

TL;DR: The scarcity of the C282Y mutation in other populations accounts for the lack of HH in non-Europeans.