T
T. M. Wengenack
Researcher at University of Rochester
Publications - 6
Citations - 179
T. M. Wengenack is an academic researcher from University of Rochester. The author has contributed to research in topics: Ischemia & Hippocampal formation. The author has an hindex of 4, co-authored 6 publications receiving 173 citations.
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Journal ArticleDOI
Selective vulnerability and early progression of hippocampal CA1 pyramidal cell degeneration and GFAP-positive astrocyte reactivity in the rat four-vessel occlusion model of transient global ischemia
J. M. Ordy,T. M. Wengenack,P. Bialobok,Paul D. Coleman,Patricia M. Rodier,R.B. Baggs,W. P. Dunlap,B. Kates +7 more
TL;DR: The results provided quantitative data on the effects of specific 4-VO criteria and durations on selective, bilaterally symmetrical CA1 pyramidal cell damage, differential CA1-CA3 cell vulnerability, and prospect of a "therapeutic window" for pharmacological treatment of CA1 neuronal injury.
Book ChapterDOI
Pharmacological Effects of Remacemide and MK-801 on Memory and Hippocampal CA1 Damage in the Rat Four-Vessel Occlusion (4-VO) Model of Global Ischemia
TL;DR: The 4-VO model is widely used for studying the phenomenon of “selectively vulnerable, delayed onset” pathophysiology of hippocampal CAl neurons in global ischemia and there is credible evidence for a critical role of the hippocampus in a specific type of spatial, representational, or episodic memory.
Book ChapterDOI
Visual Acuity, Aging, and Environmental Interactions: A Neuroscience Perspective
TL;DR: In this paper, it was suggested that impairments in visual functions and the incidence of ocular pathologies appear closely associated with advancing age (Birren and Williams, 1982), although cross-sectional studies may overestimate age declines in various visual functions such as acuity, contrast sensitivity, adaptation, stereopsis and stereopsis.
Journal Article
Phenotype and age differences in blood gas characteristics, electrolytes, hemoglobin, plasma glucose and cortisol in female squirrel monkeys.
TL;DR: Differences in blood gases, electrolytes, hematology, blood glucose and cortisol among young and old Bolivian (Roman type) and Colombian (Gothic type) phenotypes of the squirrel monkey are compared.
Book ChapterDOI
Vascular and Cellular Protein Changes Precede Hippocampal Pyramidal Cell Loss Following Global Ischemia in the Rat
TL;DR: No studies have assessed the BBB permeability of hemoglobin following global ischemia, which is especially relevant since hemoglobin has been reported to generate free radicals and be neurotoxic in vitro and in vivo.