T
T. Melander
Researcher at Karolinska Institutet
Publications - 34
Citations - 5347
T. Melander is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Galanin & Neuropeptide. The author has an hindex of 23, co-authored 34 publications receiving 5302 citations.
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Journal ArticleDOI
Distribution of galaninlike immunoreactivity in the rat central nervous system
TL;DR: The localization of galanin (GAL) immunoreactive (IR) neuronal structures in the rat central nervous system has been investigated by using the indirect immunofluorescence technique and structures seen in high concentrations in the hypothalamus, medulla oblongata, and spinal cord.
Journal ArticleDOI
Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS
T. Melander,Tomas Hökfelt,Åke Rökaeus,A.C. Cuello,Wolfgang H. Oertel,A. Verhofstad,Menek Goldstein +6 more
TL;DR: The present results demonstrate that a GAL-like peptide is present in many systems containing other neuroactive compounds, including dopamine, norepinephrine, 5-HT, GABA, and vasopressin.
Journal ArticleDOI
Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy.
TL;DR: Some primary sensory neurons react to transection of their peripheral branches by expressing increased GAL levels, and this reaction has been described by other groups for vasoactive intestinal polypeptide.
Journal ArticleDOI
A galanin-like peptide in the central nervous system and intestine of the rat.
Åke Rökaeus,T. Melander,Tomas Hökfelt,Jan M. Lundberg,Kazuhiko Tatemoto,Mats Carlquist,V. Mutt +6 more
TL;DR: It is reported that GAL-like immunoreactivity occurs in wide-spread systems in the rat CNS and intestine.
Journal ArticleDOI
Galanin inhibits acetylcholine release in the ventral hippocampus of the rat: histochemical, autoradiographic, in vivo, and in vitro studies.
Gilberto Fisone,Chun F. Wu,Silvana Consolo,Öie Nordström,Niclas Brynne,Tamas Bartfai,T. Melander,Tomas Hökfelt +7 more
TL;DR: It was shown that galanin, in a concentration-dependent manner, inhibited the evoked release of acetylcholine in the ventral, but not in the dorsal, hippocampus of the rat, suggesting that a large proportion of them is localized on cholinergic nerve terminals of septal afferents.