T
T. Mohandas
Researcher at UCLA Medical Center
Publications - 13
Citations - 618
T. Mohandas is an academic researcher from UCLA Medical Center. The author has contributed to research in topics: Gene & X chromosome. The author has an hindex of 12, co-authored 13 publications receiving 613 citations. Previous affiliations of T. Mohandas include University of California, Los Angeles.
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Journal ArticleDOI
Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes
Robert S. Sparkes,Melvin I. Simon,V H Cohn,R E Fournier,J Lem,Ivana Klisak,C. Heinzmann,Cila Blatt,M Lucero,T. Mohandas +9 more
TL;DR: These results should lead to studies of genetic loci syntenic with the PrP gene, which may play a role in the pathogenesis of prion diseases or other degenerative neurologic disorders.
Journal Article
The gene for human liver arginase (ARG1) is assigned to chromosome band 6q23.
Robert S. Sparkes,G J Dizikes,Ivana Klisak,Wayne W. Grody,T. Mohandas,C. Heinzmann,Susan Zollman,Aldons J. Lusis,Stephen D. Cederbaum +8 more
TL;DR: The human liver arginase gene, whose deficiency is responsible for argininemia (McKusick no. 20780), has been assigned to 6q23 through a combination of somatic cell hybrid analysis and in situ hybridization using a 1,550-base pair human DNA probe for this gene.
Journal ArticleDOI
Expression of a novel transcript of the myelin basic protein gene.
K Kitamura,S L Newman,Celia W. Campagnoni,Joseph M. Verdi,T. Mohandas,Vance Handley,Anthony T. Campagnoni +6 more
TL;DR: The results suggest that the structure of the MBP gene is more complex than originally thought, containing at least two more exons and there appears to be at least one moreMBP gene promoter that directs the synthesis of a subset of MBP mRNAs with a unique 5′‐untranslated region.
Journal Article
Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome.
TL;DR: Mouse-human cell hybrid clones retaining an inactive translocated chromosome involving the human X and 13 were isolated and genetic evidence for the spreading of inactivation into the autosomal segment in an inactive human X-autosome translocation is provided.
Journal ArticleDOI
Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen→q131) and adenosine deaminase (q131→qter) on chromosome 20
TL;DR: The gene loci for S-adenosylhomocysteine hydrolase (AHCY) and adenosine deaminase (ADA), two enzymes with related metabolic functions, have been assigned to human chromosome 20.