T
Tadashi Nishiwaki
Researcher at Nagoya City University
Publications - 6
Citations - 633
Tadashi Nishiwaki is an academic researcher from Nagoya City University. The author has contributed to research in topics: Esophageal cancer & Cancer. The author has an hindex of 5, co-authored 6 publications receiving 608 citations.
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Journal ArticleDOI
Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy.
Joji Kato,Yoshiyuki Kuwabara,Masami Mitani,Noriyuki Shinoda,Atsushi Sato,Tatsuya Toyama,Akira Mitsui,Tadashi Nishiwaki,Satoru Moriyama,Junzo Kudo,Yoshitaka Fujii +10 more
TL;DR: The results suggest that survivin expression may provide prognostic information in patients with esophageal cancer.
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Expression of PTTG (pituitary Tumor transforming gene) in esophageal cancer
Yasuyuki Shibata,Nobuhiro Haruki,Yoshiyuki Kuwabara,Tadashi Nishiwaki,Joji Kato,Noriyuki Shinoda,Atsushi Sato,Masahiro Kimura,Hiroshi Koyama,Tatsuya Toyama,Hideyuki Ishiguro,Junzo Kudo,Yukio Terashita,Shigeru Konishi,Yoshitaka Fujii +14 more
TL;DR: In this paper, a reverse transcription polymerase chain reaction was performed on 48 esophageal cancer specimens and the results showed that PTTG1 mRNA expression was significantly higher in tumors with higher pathological stage (IV vs 0-III, P = 0.0442) or more extensive lymph node metastasis (pathological N factor; N4 vs N0-3, P
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Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer
Yasuyuki Shibata,Nobuhiro Haruki,Yoshiyuki Kuwabara,Hideyuki Ishiguro,Noriyuki Shinoda,Atsushi Sato,Masahiro Kimura,Hiroshi Koyama,Tatsuya Toyama,Tadashi Nishiwaki,Junzo Kudo,Yukio Terashita,Shigeru Konishi,Hironori Sugiura,Yoshitaka Fujii +14 more
TL;DR: It is reported here that a significant proportion of human esophageal cancer has loss of expression of Chfr gene, and aberrant hypermethylation of the promoter region of this checkpoint gene is found in four of 15 esophagal cancer cell lines and in seven of 43 primary cancers.
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Decreased peroxisome proliferator-activated receptor gamma gene expression is correlated with poor prognosis in patients with esophageal cancer.
Yukio Terashita,Hidefumi Sasaki,Nobuhiro Haruki,Tadashi Nishiwaki,Hideyuki Ishiguro,Yasuyuki Shibata,Junzo Kudo,Shigeru Konishi,Joji Kato,Hiroshi Koyama,Masahiro Kimura,Atsushi Sato,Noriyuki Shinoda,Yoshiyuki Kuwabara,Yoshitaka Fujii +14 more
TL;DR: The mRNA expression level of PPAR gamma may be a marker of prognosis after operation in esophageal cancer patients and this work examined the correlation between the expression of PPar gamma mRNA with prognosis of esophagesia cancer patients.
Journal ArticleDOI
Aberrant nuclear localization of β-catenin without genetic alterations in β-catenin or Axin genes in esophageal cancer
Junzo Kudo,Tadashi Nishiwaki,Nobuhiro Haruki,Hideyuki Ishiguro,Yasuyuki Shibata,Yukio Terashita,Hironori Sugiura,Noriyuki Shinoda,Masahiro Kimura,Yoshiyuki Kuwabara,Yoshitaka Fujii +10 more
TL;DR: A fraction of esophageal squamous cell carcinomas have abnormal nuclear accumulation of β-catenin accompanied with increased cyclin D1 expression, and mutational change was found in β-Catenin exon 3 in the four cases with nuclear β- catenin staining.